Since its release, the Krasr website and the Amazon page for
Comedo Suction Microdemabrasion Machine have been flooded with positive reviews.
Regarding DCIS associated with the invasive carcinomas, as might be expected, the
comedo type was more likely associated with invasive carcinomas with high RS.
Tumor size, grade, and
comedo status did not appear to be strongly associated with endocrine therapy initiation.
IDC was found to be most prevalent compared to other histological types such as invasive lobular and other types such as papilloma, paget's disease, metastatic carcinoma, focal invasion
comedo type, and ductal papilloma with mucinous carcinoma.
In our case mixed pattern of tubular and lobular carcinoma was seen with large foci of
comedo, cribriform DCIS.
Motoyoshi, "Enhanced
comedo formation in rabbit ear skin by squalene and oleic acid peroxides," British Journal of Dermatology, vol.
Cosmetics, and some moisturisers, too, can cause acne by blocking the pores with a greasy layer that encourages the proliferation of bacteria, providing the ideal conditions for comedones, or blackheads, to develop (a
comedo being the basic acne lesion).
Histopathology showed anaplastic tumor cells arranged in irregular, lobular formation with central necrosis giving it a
comedo pattern.
A family history of early onset sarcoma, glioma or other childhood tumours should be sought and if the breast cancer is a
comedo ductal carcinoma in situ (DCIS), or has occurred within an area of
comedo DCIS, TP53 testing with genetic counselling should be offered.
Solid, micropapillary and
comedo types were present in all 3 biopsies.
DCIS is a heterogeneous group of lesions: in the past the classification was based on the architectural or growth patterns (
comedo, solid, cribriform, micropapillary); nowadays it is based on factors that have proved especially useful in predicting the risk for local recurrence.