comparative genomic hybridization


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comparative genomic hybridization

[kəm¦par·əd·iv jə‚nō·mik ‚hī·brəd·ə′zā·shen]
(genetics)
A method that uses fluorescence in situ hybridization and comparison of the strength of hybridization signal to determine any differences in copy number of deoxyribonucleic acid sequences anywhere in the nuclear genome.
References in periodicals archive ?
Comparative genomic hybridization was performed to further characterize copy number alterations in the tumor.
Introducing array comparative genomic hybridization into routine prenatal diagnosis practice: a prospective study on over 1000 consecutive clinical cases.
Clinical application of array-based comparative genomic hybridization for the identification of prognostically important genetic alterations in chronic lymphocytic leukemia.
Aneuploidy detection in single cells using DNA array-based comparative genomic hybridization.
Microarray-based comparative genomic hybridization and its applications in human genetics.
The initial certification is for Comparative Genomic Hybridization (aCGH), which is an application used by researchers to discover and detect genomic copy number variations within specific genomes.
Although preimplantation genetic screening (PGS) allows examination of only about half of the chromosomes in a 3-day embryo, the new technique, known as comparative genomic hybridization (CGH), can evaluate all chromosomes in newly fertilized oocytes (zygotes), Elpida Fragouli, Ph.
Yet they are genetically melanoma as demonstrated using comparative genomic hybridization and fluorescent in situ hybridization, Dr.
Dr Fishel, a former pupil of King David School, Childwall, said: "We are delighted to announce the world's first pregnancy using real-time polar body array Comparative Genomic Hybridization (CGH) and the baby is due later in the spring.
Dan Marshak, vice president and chief scientific officer of PerkinElmer, described the use of comparative genomic hybridization for verifying the chromosomal stability of stem cell lines over time.
and Baylor College of Medicine today announced that Baylor has obtained a non-exclusive worldwide license to a number of Affymetrix patents covering comparative genomic hybridization (CGH) microarray services in Clinical Laboratory Improvement Amendments (CLIA) environments.
Regarding the story about using comparative genomic hybridization on preimplantation cells ("It's a boy
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