concatamer


Also found in: Medical.

concatamer

[kən′kad·ə·mər]
(cell and molecular biology)
Two or more identical linear molecules (for example, deoxyribonucleic acid and ribonucleic acid) covalently linked in tandem.
References in periodicals archive ?
(The variation involves a virus-encoded DNA nicking enzyme which cuts and separates the individual viral genomes from the resulting concatamer.) The mechanism, however, also has been adapted by clever molecular biologists, in the LAMP technique.
In immunoRCA, the 5' end of an oligonucleotide primer is attached to an antibody; thus, in the presence of circular DNA, DNA polymerase, and nucleotides, the rolling circle reaction produces a concatamer of circle DNA sequence copies that remain attached to the antibody.
In this "immunoRCA", the 5' end of a RCA primer is attached to an antibody; thus, in the presence of circular DNA, DNA polymerase, and nucleotides, the rolling circle reaction produces a concatamer of circular DNA sequence copies that remain attached to the antibody.
Chai et al., "Electrochemical immunosensor for detecting the spore wall protein of Nosema bombycis based on the amplification of hemin/G-quadruplex DNAzyme concatamers functionalized Pt at Pd nanowires," Biosensors and Bioelectronics, vol.
When dPCR is used, there is a unique challenge associated with quantifying sequences that may occur as concatamers (repeats of the same sequence that are present on the same molecule); concatameric sequences cannot be measured individually in different partitions.