congenital heart disease

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congenital heart disease,

any defect in the heartheart,
muscular organ that pumps blood to all parts of the body. The rhythmic beating of the heart is a ceaseless activity, lasting from before birth to the end of life. Anatomy and Function

The human heart is a pear-shaped structure about the size of a fist.
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 present at birth. There is evidence that some congenital heart defects are inherited, but the cause of most cases is unknown. One known cause is infection of the mother with the rubellarubella
or German measles,
acute infectious disease of children and young adults. It is caused by a filterable virus that is spread by droplet spray from the respiratory tract of an infected individual.
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 (German measles) virus during the first trimester of pregnancy. Among the most common congenital heart disorders are malformations in the valves and the persistence of structures that are normally closed off at birth, i.e., the ductus arteriosis (the fetal blood vessel that shunts blood from the pulmonary vein to the aorta, bypassing the heart) and the foramen ovale (the opening between the left and right atria of the fetal heart). If the malformation is severe, it will produce various symptoms of insufficient heart function, such as cyanosis (a bluish tinge to the skin), dyspnea (difficulty in breathing), fatigue, and abnormal heartbeat; valvular deformities predispose the patient to bacterial infection of the endocardium (see endocarditisendocarditis
, bacterial or fungal infection of the endocardium (inner lining of the heart) that can be either acute or subacute. In the acute form the symptoms (fever, malaise, fatigue, weight loss, anemia) are directly related to the presence of an active infection that runs
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). Less severe malformations may not produce noticeable symptoms until later in life, and some may not require any medical attention. Many congenital heart defects that are debilitating can be corrected surgically. Other congenital anomalies, such as Down syndromeDown syndrome,
congenital disorder characterized by mild to severe mental retardation, slow physical development, and characteristic physical features. Down syndrome affects about 1 in every 730 live births and occurs in all populations equally.
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, are present in about 20% of cases of congenital heart disease. See also heart diseaseheart disease,
any of several abnormalities of the heart and its function in maintaining blood circulation. Heart disease is the cause of approximately half the deaths in the United States each year.
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References in periodicals archive ?
Impact of congenital heart disease on the family: Preliminary report.
Smith Professor of Genetics and Medicine at Brigham and Women's Hospital and a Howard Hughes Medical Institute investigator, these findings could lead to early testing that would help identify newborns with congenital heart disease who are at high risk of neurodevelopmental difficulties.
Data source: An outpatient adult congenital heart disease clinic in which 134 patients attending were assessed for anxiety, depression, and quality of life using validated instruments.
Pediatric cardiologists, heart surgeons, anesthesiologists, nurses and perfusionists from nearly every state and over 20 countries will discuss new treatments for children in heart failure, neurodevelopment in children who have congenital heart disease, innovation and challenges in the management of children with single ventricle, and adult congenital heart disease.
The BHF across the UK funds over PS14m into congenital heart disease research, which will ultimately help children in Wales, and this year they need the help of people in Cardiff to raise more.
The new review will consider the whole lifetime pathway of care for people with congenital heart disease.
Most newborns who leave hospitals without being tested die early since the congenital heart disease is not discovered," she said.
5 lakh infants are born in India with congenital heart disease," Dr Murtaza Chishti, chief cardiac surgeon of the Mahatma Gandhi Cardiac and Critical Care Centre told, The Indian Express Reported.
A comprehensive approach to congenital heart diseases.
Keavney said that his team found that a common genetic variation near a gene called Msx1 was strongly associated with the risk of a particular type of congenital heart disease called atrial septal defect or hole in the heart.
Every year, 5,000 babies are born with congenital heart disease.
The prevalence of congenital heart disease in Europe was recently reported in two major papers.

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