Methemoglobinemia

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Related to congenital methemoglobinemia: methemoglobin test

methemoglobinemia

[¦met‚hē·mə·glō·bə′nē·mē·ə]
(medicine)
The presence of methemoglobin in the blood.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Methemoglobinemia

 

the appearance of methemoglobin in the blood as a result of the toxic effect of various chemical substances (nitrates and nitrites, aniline, pyridine) that are capable of converting hemoglobin to methemoglobin (MtHb) upon entering the body through the skin, digestive tract, or lungs. With considerable methemoglobinemia, oxygen starvation, or hypoxia, may result. Methemoglobin may be excreted with the urine (methemoglobinuria); this is sometimes damaging to the kidneys. Methemoglobinemia is treated with antidotes (methylene blue, ascorbic acid) and oxygen therapy.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The diagnosis of congenital methemoglobinemia is based on the level of the intracellular cytochrome b5 reductase enzyme.
Congenital methemoglobinemia: a rare cause of cyanosis in the newborn-a case report".
Prophylactic methylene blue in a patient with congenital methemoglobinemia. Can J Anesth 2005; 52:258-261.
The methemoglobinemia observed in this patient (Table 1) most likely had an iatrogenic cause; there is little clinical likelihood of congenital methemoglobinemia (1).

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