consensus sequence

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consensus sequence

[kən′sen·səs ‚sē·kwəns]

(genetics)

An average nucleotide sequence; each nucleotide is the most frequent at its position in the sequence.

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gene

References in periodicals archive ?

Recently it was confirmed that consensus sequences forming stable G-quadruplex structures are responsible for RNA replication and inhibition of protein translation of hepatitis C virus [14].

Putative HIV and SIV G-Quadruplex Sequences in Coding and Noncoding Regions Can Form G-Quadruplexes

Partial sequences from the NCBI DNA sequence database that match segments of the consensus sequence shown in Fig.

A Case Study: Was Private William Braine of the 1845 Franklin Expedition a Victim of Tuberculosis?

Briefly, consensus sequences from the WSB, PWK, and CAST strains were mapped to the alignment and gaps filled with Ns.

Chromosome 1 Sequence Analysis of C57BL/6J-Chr1[KM] Mouse Strain

Two individuals were found to have an identical consensus sequence for the genotyped C*14:02:01 allele, which harbors 2 distinct polymorphisms, resulting in the reporting of only a single novel allele sequence.

Generation of Full-Length Class I Human Leukocyte Antigen Gene Consensus Sequences for Novel Allele Characterization

RT-PCR was performed to confirm our speculation about the FAMLF consensus sequence. Two peripheral blood samples from AL patients were amplified by RT-PCR and a specific band of expected size (2214 bp) was obtained, as well as an unexpected 429-bp band (Figure 1).

The consensus sequence of FAMLF alternative splice variants is overexpressed in undifferentiated hematopoietic cells

According to the results of multiple alignments of all the obtained consensus sequences, it was possible to detect differences between the species T.

Molecular identification of Trichogramma species from regions in Brazil using the sequencing of the ITS2 region of ribosomal DNA/Identificacao molecular de especies de Trichogramma de regioes do Brasil utilizando o sequenciamento da regiao ITS2 do DNA ribossomal

The higher the depth of read coverage, the better statistical strength this consensus sequence has, as correct reads at any individual position increasingly outnumber individual read errors.

In-depth coverage: some useful NGS terms

In Escherichia coli the SOS gene network is under control of the RecA protein which, as consequence of DNA damage, induces the autoproteolysis of LexA repressor which binds the 16 bp palindromic consensus sequence named LexA-binding box.

Curcumin inhibits the SOS response induced by levofloxacin in Escherichia coli

The alignment file created is then used to construct a consensus sequence using the IUPAC degenerate nucleotide codes [34].

Large scale explorative oligonucleotide probe selection for thousands of genetic groups on a computing grid: application to phylogenetic probe design using a curated small subunit ribosomal RNA gene database

The major difference is that it begins with a consensus sequence containing degenerate bases and selects primers with fewer than 3 or 4 degenerate bases, so that in the end a majority of strains are amplified, but it does not require primers to amplify all strains.

Multiplex degenerate primer design for targeted whole genome amplification of many viral genomes

This T-cell epitope is observed in all the serological variants of DEN, with each serotype having its distinct consensus sequence for the epitope.

Positive selection and evolution of dengue type-3 virus in the indian subcontinent