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Med any sensation or change in bodily function experienced by a patient that is associated with a particular disease
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



an indication of a phenomenon, for example, of a disease. Many types of symptoms are distinguished in medicine. Constitutional symptoms characterize diseases of varying genesis and include weakness and increases in body temperature. Pathognomonic symptoms indicate a definite nosologic form; a stabbing pain in the epigastric region, for example, is typical of a perforating gastric ulcer. Subjective symptoms are only revealed upon questioning the individual, and objective symptoms are readily observable through examination, palpation, percussion, auscultation, and laboratory and instrumental diagnostic methods. Signal symptoms are the precursors of a disease. They include early symptoms, such as chest pains with pneumonia, and late symptoms, such as peritoneal irritation with cholecystitis.

A disease is said to be atypical if its characteristic symptoms are absent from the very beginning; an example of an atypical disease is the painless form of myocardial infarction. Modern therapeutic measures and protective inoculations can substantially alter the symptoms of a disease and even cause them to disappear. Diagnosis and prognosis are based on a knowledge of all of the symptoms of a disease.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


A phenomenon of physical or mental disorder or disturbance which leads to complaints on the part of the patient.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Our patient presented with bilateral lower limb skin rash with systemic involvement marked by peripheral neuropathy, proteinuria, and constitutional symptoms. The differential diagnoses considered were a systemic vasculitis, systemic infection, or rarely an internal malignancy with systemic manifestations.
The OIS patients with constitutional symptoms and a longer disease course had worse visual function.
The nonspecific features including pain, swelling, and localized tenderness may be present, but pyrexia or constitutional symptoms are usually absent.
In our case described, a pregnant lady presenting with chronic constitutional symptoms should have been thoroughly investigated for possible causes, at primary contact, with referral to the obstetrics and medical teams for specialist care.
His joint pain and constitutional symptoms of fever and anorexia have subsided and he has regained his lost weight and feeling of wellbeing.
The authors suggested factors that should prompt investigation for underlying neoplasm including constitutional symptoms, abnormal circulating cells on peripheral blood smear, cytopenias, an elevated ESR, lymphadenopathy or organomegaly on clinical examination, and masses on imaging.
The most common physical signs and symptoms of MS include constitutional symptoms, muscle weakness, motor and autonomic spinal cord symptoms, paresthesias, and vision changes.
Laboratory investigations of his constitutional symptoms were largely unremarkable.
I'm pretty diligent about testing teens admitted with unexplained fever, vague constitutional symptoms, and those with symptoms that suggest another STI.
Due to relatively mild general constitutional symptoms, we started the patient on colchicine and sustained a low dose of prednisone with rapid improvement of rash.
After 10 months of treatment with multibacillary multi drug therapy (MB-MDT); he had an unusual Type 2 lepra reaction (T2R) with constitutional symptoms, perichondritis, epididymo-orchitis, bilateral pedal edema and tender inguinal lymph nodes (Figure: 3); but without erythema nodosum leprosum (ENL) and neuritis.
Notably, the patient was subjectively doing quite well and reported no chills, fatigue, or other constitutional symptoms. Physical examination was unremarkable except for some bad teeth and oral care.

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