constitutive

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constitutive

1. having power to enact, appoint, or establish
2. Chem (of a physical property) determined by the arrangement of atoms in a molecule rather than by their nature
3. Biochem (of an enzyme) formed continuously, irrespective of the cell's needs
References in periodicals archive ?
Here Ritchie develops and motivates a structuralist ontology of social groups centered on social structures (that is, networks of relations that are constitutively dependent on social factors).
The functional significance of this was explored using an MHC-II-negative orthotopic model cell line unlikely to induce expression of MHC-II when treated with interferon-gamma in culture; MHC-class-II transactivator (CIITA), the master regulator of MHC-II, was used to transduce the cells, resulting in cells that were "constitutively 100% class II+."
For Marie to be unopposed to stealing involves her constitutively possessing the corresponding negative dispositions, such as
The model was tested in two different human cell lines: MCF-7, an estrogen responsive cell line derived from metastatic human breast adenocarcinoma, which is known to express PTGS2 (12), and HEK293FT, a highly transfectable clonal isolate derived from human embryonal kidney cells HEK293, which does not constitutively express PTGS2 (13).
High expressions of mRNA as the genes were driven by a constitutively expressing 35S promoter.
In contrast, overexpression of constitutively active form of PI3K [21-23] or exogenous addition of cell-permeable derivatives of PIP3 induces insulin-independent GLUT4 translocation [24].
In a previous study, transformation of retrovirus driver leukemia cells with constitutively active (CA) STAT5 signaling was employed to achieve second hit and leukemic transformation ability [13].
To determine the nature of the expression of enzyme, either it expresses constitutively or inducible an experiment was conducted in LB broth in the absence or presence of chlorpyrifos (0.75 mM) respectively.
(1) Vemurafenib is a small molecule inhibitor that binds the active form of BRAF and is highly selective for the constitutively active [BRAF.sup.V600E] mutant over wild-type BRAF.
1B, HN3 and FaDu cells relatively overexpressed constitutively active STAT3 as compared to other tumor cells.
* Alteration of secondary messenger (4) so it's constitutively active, thus constantly relaying a signal from (3) that's not really there; or