contact inhibition


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contact inhibition

[′kän‚takt in·ə′bish·ən]
(cell and molecular biology)
Cessation of cell division when cultured cells are in physical contact with each other.
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References in periodicals archive ?
Contact inhibition is the impediment of excessive growth of cells by neighboring cells.
Eviatar Nevo, from the Institute of Evolution at the University of Haifa, said that contact inhibition, a powerful anticancer mechanism, discovered by the Rochester team, arresting cell growth when cells come into contact with each other, is lost in cancer cells.
5 to over 2, genetic instability, and the high level of membrane-bound and secreted proteins responsible for invasiveness and loss of contact inhibition.