contiguous gene syndrome


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contiguous gene syndrome

[kən¦tig·yə·wəs ′jēn ′sin′drōm]
(genetics)
A characteristic complex phenotype produced by deletion of a short chromosome segment, resulting from haplo-insufficiency of several genes in the deleted segment.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
H Wreschner, "C4orf48, a gene related to the Wolf-Hirschhorn contiguous gene syndrome, codes for a novel secreted protein linked to cell differentiation processes," Journal of Proteomics & Bioinformatics, vol.
Complex glycerol kinase deficiency-X-linked contiguous gene syndrome involving congenital adrenal hypoplasia, glycerol kinase deficiency, muscular Duchenne dystrophy and intellectual disability (IL1RAPL gene deletion).