Based on the cut-off value of 0.15 proposed by geNorm program, four reference genes are necessary to obtain the lowest control genes
in the tested samples of both whole blood and PBMC.
(16) Each day, 8 samples were tested in duplicate (both BCR-ABL1 and control gene
Air pollutants or cigarette smoke, both exhibiting oxidative properties, specifically alter the expression levels of tumor suppressor genes such as p53 and p21 and of the cell cycle control gene
CCND1 in human and rodent in vitro bronchial cell culture models.
By engineering ZFPs so that they can recognize a specific gene, Sangamo has created ZFP transcription factors (ZFP TFs) that can control gene
expression and, consequently, cell function.
[[beta].sub.2]-microglobulin was used as an internal reference control gene
. The sequences for primers used in this study are listed in Table 1.
Gene regulatory proteins control gene
expression in developmental and cellular processes of many organisms.
Although initial advances have relied primarily on the measurement of protein-coding messenger RNAs, it is well-known that non-coding RNAs are also instrumental in regulating cell function and represent an exciting and growing class of diverse molecules that can control gene
expression at both the transcriptional and post-transcriptional levels.Using microfluidics technology, Fluidigm developed the C1 Total RNA Seq application to enable simultaneous detection of mRNAs and ncRNAs at single-cell resolution.
These associated regions probably represent regulatory elements that control gene
expression," Horsfield said.
Diabetes drugs called thiazolidinediones (TZDs) control gene
expression by targeting a factor called PPAR gamma.
Similar to other work in the field of optogenetics, this new method re-lies on light to control gene
It can allow scientists to control gene
expression and selectively turn genes on or off.