Longer-lived positron emitters include zirconium-89 ([sup.89]Zr, [T.sub.1/2] = 78.41 h), copper-64 ([sup.64]Cu, [T.sub.1/2] = 12.7 h), and iodine-124 ([sup.124]I, [T.sub.1/2] = 100.22 h).
Copper-64. Copper-64 has a relatively long half-life (12.7 h) and can undergo electron capture ([epsilon], 43.8%), [[beta].sup.+] emission to [sup.64]Ni (17.8%), and [[beta].sup.-] emission to 64Zn (38.4%) .
Copper-64 can be effectively produced in nuclear reactors and accelerators.
(28), (29) As part of these studies, we used an absorption test for copper-64
(a simple copper salt) and showed that a minimum of 15% of ingested copper-64
bypasses the liver and adds immediately to the free copper pool of the blood.
Also on Saturday, Iran started production of copper-64 radiomedicine which puts the country among the first four producers of this radiomedicine in the world.
Copper-64 is a radioactive nuclide of copper which has unique decay properties making it useful in nuclear medicine for both imaging and therapy.
Last month, the National Cancer Institute issued Welch a grant that will subsidize his team's making of copper-64
for itself and other medical researchers around the country.
These chelators and their derivatives have been successfully used to label a number of peptides and antibody fragments with copper-64 [24-27].
Anderson, "Radiolabeling of TETA- and CB-TE2A-conjugated peptides with copper-64," Nature Protocols, vol.