corepressor


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Related to corepressor: inducer, coactivator

corepressor

[¦kō·ri‚pres·ər]
(cell and molecular biology)
A certain metabolite which, through combination with a repressor apoprotein produced by a regulator gene, can cause the binding of the protein to the operator gene region of a deoxyribonucleic acid chain.
References in periodicals archive ?
10] Human genes: CD117, synonym for KIT (KIT proto-oncogene receptor tyrosine kinase); EGFR, epidermal growth factor receptor; ALK, anaplastic lymphoma receptor tyrosine kinase; HER2, synonym for EBBR2 (erb-b2 receptor tyrosine kinase 2); BRAF, B-Raf proto-oncogene, serine/threonine kinase; KRAS, KRAS proto-oncogene, GTPase; CEBPA, CCAAT/enhancer binding protein alpha; APC,APC, WNTsignaling pathway regulator; RB1, RB transcriptional corepressor 1; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
AtERF7, an APETALA2/EREBP-type transcription factor that plays an important role in abscisic acid response, interacts with the Arabidopsis homologue of the global corepressor of transcription AtSin3, which in turn may interact with HDA19 and enhance the transcriptional repression activity (Song et al.
Regulation of nuclear coactivator and corepressor expression in mouse cerebellum by thyroid hormone.
Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions.
I aim at investigating conditions and the consequences of activation of a particular copy of the MERmaid transposon located in the Sin3B transcriptional corepressor, frequently observed in cancer.
PROX1, Prospero protein homeobox Corepressor of hepatocyte nuclear 1 (1) factor 4a which plays an important role in [beta]-cell development GCKR, Glucokinase regulator (2) Regulatory protein that inhibits glucokinase.
The team knocked out the gene for a protein called nuclear receptor corepressor 1 (NcoR1) in the muscles of mice.
The study found that by genetically manipulating the offspring of these species, the researchers were able to suppress the NCoR1 corepressor, which normally acts to inhibit the buildup of muscle tissues.
Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription.
1 his tone deacetylase complex; transcription corepressor activity corepressor activity 215378_at Ankyrin repeat and KH domain 5q31.
Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters.
Weaver's team found that cancer cells grown in a 3-D environment had higher levels of a protein called nuclear receptor corepressor 2 (N-CoR2) than cells in flat dishes.