AtERF7, an APETALA2/EREBP-type transcription factor that plays an important role in abscisic acid response, interacts with the Arabidopsis homologue of the global corepressor
of transcription AtSin3, which in turn may interact with HDA19 and enhance the transcriptional repression activity (Song et al.
MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor
The researchers say their results are a milestone in our understanding of certain fundamental mechanisms of living organisms, in particular the little-studied role of corepressors
Alternatively, the binding of a SERM to an estrogen receptor may result in a different conformational change, making the binding of the coactivators more difficult or even causing the binding of a corepressor
Another protein, called Lxc (formerly called Bof and located within the ImmT region of P1), enhances binding of C1 repressor to certain operator sites along the DNA and is sometimes referred to as a corepressor
Histone deacetylases (HDACs) 1 and 2 are highly conserved enzymes that help regulate chromatin structure as the core catalytic components of corepressor
complexes (Brunmeir et al.
CtBP is an NAD+-regulated dehydrogenase.
Their research revealed a new and previously unsuspected role for nuclear receptor corepressor
(NCoR), a transcriptional coregulatory protein found in a wide variety of cells.
Unlike coactivators, AR corepressor
proteins can form complexes with AR and inhibit the transcription of AR-regulated genes.
A Newly Identified Role of Nuclear Receptor Corepressor
, SMRT (Silencing Mediator of Retinoid and Thyroid) in Improving Hyperglycemia and Insulin Sensitivity in Obese and Diabetic Mice (Late-Breaking Poster) Authors: S.
Studies have identified about 30 different estrogen-receptor-enhancing, or coactivator, proteins, and a few receptor-suppressing, or corepressor
48 DEPDC1 DEP domain Transcriptional containing 1 corepressor