Perfusion

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perfusion

[pər′fyü·zhən]
(physiology)
The pumping of a fluid through a tissue or organ by way of an artery.

Perfusion

 

a method of passing physiological solutions, blood, blood substitutes, or other fluids through the blood vessels of an organ, a part of the body, or the entire body. Perfusion may be performed on organs completely removed from the body or on organs within the body but isolated from the general vascular system. Widely used in experimental physiology, it permits preservation of the vital activities of organs for a certain period, enabling the study of organ functions and of the effect of hormones, mediators, enzymes, and medicinal substances on physiological systems and the entire body. The method is used in various branches of surgery, including transplantation of organs and tissues. Perfusion of the entire body is used, for example, during heart surgery.

The term “perfusion” also designates the supplying of blood to organs of the body under natural conditions (for example, perfusion of the kidneys, brain, or other organs), which is determined by the state of cardiac activity and local vascular tonus.

References in periodicals archive ?
Epinephrine increases coronary perfusion pressure by decreasing blood flow to all other organs, an effect that may persist after the restoration of pulses.
The effect of standard- and high-dose epinephrine on coronary perfusion pressure during prolonged cardiopulmonary resuscitation.
The Ang II infusion induced increases in coronary perfusion pressure in a concentration-dependent fashion in all experimental groups (Figure 3(a)).
Our results on cardiac function showed a decrement in coronary perfusion pressure and left ventricular performance in CKD group.
Under these conditions, TGS significantly and dose-dependently increased coronary perfusion flow rate, indicating the dilation of coronary artery.
In conclusion, we for the first time demonstrated that TGS can elevate coronary perfusion flow of isolated rat hearts in Langendorff system under either basal perfusion or I/R injury condition, a consequence of coronary artery dilation, which also protected heart tissues from I/R injury.
Existing predictors of successful resuscitation include coronary perfusion pressure (22,23) and end-tidal C[O.
Also presented at this years ESC was an abstract entitled, "Improved stress radionuclide coronary perfusion and exercise capacity after enhanced external counterpulsation," by lead author, Dr.
These include the reduction or elimination of angina symptoms through increased coronary perfusion and enhanced development of collateral circulation in both diabetic and non-diabetic patients.
The New Therapeutic Approach with Enhanced External Counterpulsation in Patients with Chronic Stable Angina: Evaluation of Myocardial Flow by N-13 Ammonia PET" is the first study to investigate quantitative coronary perfusion and coronary flow reserve (CFR) associated with EECP therapy.