Histopathological Analyses of NOS Levels in Corpus Cavernosum
Epimedium brevicornum Maxim extract relaxes rabbit corpus cavernosum
through multitargets on nitric oxide/cyclic guanosine monophosphate signaling pathway.
Especially after the treatment of corpus cavernosum
abscess, complications such as ED, penile deviation, and penile curvature could develop due to fibrosis and recurrence.
Ischemic priapism is a persistent erection in which there is little or no arterial inflow to the corpus cavernosum
. Progressive hypoxia, hypercarbia, and acidosis was observed together with time-dependent changes in the corporal metabolic environment.
Previous studies with similar design showed that the number of animals is considered adequate to evaluate the expression of genes and miRNAS in the corpus cavernosum
of rats submitted to chronic alcoholism and diabetes mellitus (15-17).
Transverse Scanning Plan of Penis (Pre-Injection) showing both side Corpus cavernosum
surrounded by Echogenic Fibrous Capsule Tunica albuginea.
The corpus cavernosum
paraffin sections were immunostained with VEGF (diluted 1 : 200 Santa Cruz Biotechnologies, Santa Cruz, US), neuronal nitric oxide synthase (nNOS, diluted 1: 200 Santa Cruz Biotechnologies, Santa Cruz, CA), brain-derived neurotrophic factor (BDNF, diluted 1:200; Abcam, Cambridge, UK), nerve growth factor (NGF, diluted 1 : 200; Abcam, Cambridge, UK), stromal cell-derived factor-1 (SDF-1 diluted 1:200; Abcam, Cambridge, UK), and neuron-specific [beta]-III tubulin (diluted 1 : 200; Abcam, Cambridge, UK) and mounted with 4,6-diamidino-2-phenylindole (DAPI; Vector Laboratories Inc., Burlingame, CA) to stain the nuclei.
Caption: Figure 1: Axial T1-weighted MR images (a) demonstrate two isointense penile masses involving the left paracentral shaft base and proximal right corpus cavernosum
(solid arrows) demonstrated with enhancement (solid arrow) on axial contrast enhanced T1-weighted MR images (b).
Rupture of the corpus spongiosum and/or urethral fistula, compression of the corpus cavernosum
, and distal anesthesia.
In the clitoral region, the clitoral hood and corpus cavernosum
were dissected through an inverted V-shape incision.
Concentration of elastic system fibers in the corpus cavernosum
, corpus spongiosum, and tunica albuginea in the rabbit penis.
PDE5-Is enhance erectile function by maintaining sufficient cellular levels of cyclic guanosine monophosphate (cGMP) in both the corpus cavernosum
and its supply vessels, and the increased extension of the corporeal sinusoids allows greater blood flow.