corticotrophic

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corticotrophic

[¦kȯrd·ə‚kō¦trä·fik]
(physiology)
Having an effect on the adrenal cortex.
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References in periodicals archive ?
Curcumin dose-dependently inhibited basal VEGF secretion in corticotrope AtT20 mouse and lactosomatotrope GH3 rat pituitary tumour cells as well as in human pituitary adenoma cell cultures [93] indicating its potential as an antiangiogenic agent in pituitary adenomas.
Binding of CRH to its receptor on pituitary corticotropes induces the release of adrenocorticotropic hormone (ACTH) into the systemic circulation.
Endogenous corticosteroids may have their primary actions at brain and hypothalamic sites and synthetic glucocorticoids that do not bind to transcortin may act primarily on corticotropes and regions of brain outside the blood-brain barrier [27-29].