Psychological stress increased corticotropin-releasing hormone
mRNA and content in the central nucleus of the amygdala but not in the hypothalamic paraventricular nucleus in the rat.
(CRH) in the teleost fish Oreochromis mossambicus (tilapia): in vitro release and brain distribution determined by a novel radioimmunoassay.
CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone
, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhesus macaques.
(CRH) is a peptide with 41 amino acid residues that has been localized to paraventricular nucleus of the hypothalamus.
The dexamethasone-suppressed corticotropin-releasing hormone
stimulation (LDDST-CRH)  test was initially proposed to be more accurate in confirming hypercortisolism than the standard low-dose dexamethasone-suppression test (LDDST) for the diagnosis of Cushing syndrome (2).
In stressed mice, corticotropin-releasing hormone
, nerve growth factor, neurotensin, substance P and mast cells are recruited hierarchically to induce neurogenic skin inflammation, which inhibits hair growth.
The investigators noted both that stress-related hormones, including substance P and corticotropin-releasing hormone
, stimulate sebum production, and that, as a general principle, stress slows wound healing (Arch.
That finding suggests that the entire "fight-or-flight" stress-response system based on corticotropin-releasing hormone
(CRH) dates back to a common ancestor of vertebrates and insects.
Effects include suppression of hypothalamic gonadotropin-releasing hormone by corticotropin-releasing hormone
The new agents block the binding of corticotropin-releasing hormone
(CRH), thus interrupting the neurohormonal cascade that leads to release of cortisol, epinephrine, and norepinephrine from the adrenal glands.
As discussed in the sidebar, both corticotropin-releasing hormone
(CRH) and arginine vasopressin (AVP) can stimulate the release of adrenocorticotropic hormone (ACTH) and, hence, corticosterone release from the adrenal glands.
Although exactly how stress can lead to high blood pressure during pregnancy or premature labor is not clearly understood, elevated levels of stress-induced hormones - such as corticotropin-releasing hormone
- most likely play a role in triggering both conditions, according to lead author Dr.