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Immediately after the repair, of each tooth a cotton pellet damped with water was placed in the pulp chamber and all the teeth were stored in humidity for 72 hr at room temperature for allowed to set and mature of the repair material.
In cotton pellet induced granuloma there are three phases, a transudative phase during the first 3 h, exudative phase between 3 and 72 h and proliferative phase between 3 and 6 days.
Sterile cotton pellets (10 [+ or -] 0.5 mg) were implanted subcutaneously in the groin of mice anesthetized by 3% chloral hydrate.
penicillata (400 mg/kg) and indomethacin (10 mg/kg) on cotton pellet induced granuloma as a model of chronic inflammation; significant difference results (P < 0.05) between both groups were summarized in this table.
The 3% potassium oxalate gel (Oxa Gel, Art Dent, Araraquara, SP, Brazil) was applied to the dentin surface with a cotton pellet and left undisturbed for 2 minutes.
Table 1: Effect of Strychnos nux vomica on cotton pellet granuloma.
White mineral trioxide aggregate (MTA) (ProRoot MTA; Dentsply Tulsa Dental Specialties, Tulsa, Oklahoma, USA) was mixed with sterile saline and a 5 mm apical plug was placed and compacted followed by a moist cotton pellet and a temporary restoration (Cavit; 3M ESPE, Seefeld, Germany) (Fig 4) and cementation of a temporary FPD.
In cotton pellet granuloma model, assessing subacute anti-inflammatory action of drugs, teneligliptin, showed significant anti-granuloma effect by decreasing granuloma dry weight, thus appeared to have an action on inflammatory mediators of subacute inflammation.
It is advised to place a wet cotton pellet over the MTA in the first visit to avoid degradation by moisture as it is hydrophilic in nature and replaced by a permanent restoration at the second visit.
After radiographic control of the root-canal filling, a wet cotton pellet was applied to the pulp chamber, and the access cavity was sealed with glass ionomer cement (Ionofil Plus, Voco, Cuxhaven, Germany).
The cavity was rinsed with water and wiped with sterile cotton pellet. Group II consisted of 30 teeth for which the carious tissue was removed using the chemomechanical Papacarie technique.