Coumarin


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coumarin

[′kü·mə·rən]
(organic chemistry)
C9H6O2 The anhydride of o-coumaric acid; a toxic, white, crystalline lactone found in many plants and made synthetically; used in making perfume and soap. Also known as 1,2-benzopyrone.

Coumarin

 

a lactone of o-coumarinic acid; colorless crystals with an odor of new-mown hay. Melting point, 70°C; boiling point, 291°C. It has the following structural formula:

Coumarin is readily soluble in alcohol and ether and poorly soluble in water. It occurs in glucoside form in many plant species, for example, in sweet clover and sweet grass. Coumarin is industrially prepared from salicylic aldehyde and acetic anhydride. It serves as an odor-enhancing substance in the tobacco and perfume industries.

References in periodicals archive ?
In current our study; we report the synthesis of the poly(ethyl methacrylate) coumarin end grouped having hydroxyl (CEMA) by ATRP method.
A new benzofuran derivative glycoside and a new coumarin glycoside from roots of Heracleum dissectum Ledeb.
After the execution period, the following variables were analyzed: height of the aerial part (cm), leaf area ([cm.sup.2]), dry mass of leaves and branches (g), total dry mass (g), and coumarin content of the apical, middle, and basal segments of the plant tissue (mg [g.sup.-1]).
We demonstrate that after oral ingestion, MK-7 is more effective in both catalyzing osteocalcin carboxylation in bone and counteracting coumarin anticoagulants in the liver.
Calculations of water solubility (LogS) show that coumarin-5 has the lowest LogS value (less water soluble), while chalepin coumarin has the highest value, in accordance with logP calculations.
The flow rate was 0.6 mL/min, injection volume 50 [micro]L and the wavelength were 270 for gallic acid, 278 nm for coumarin, 327 nm for chlorogenic acid and caffeic acid, and 365 nm for quercetin, quercitrin, kaempferol and rutin.
Coumarin and its derivatives have been known for a long time, yet their vital role in plant and animal systems has not been thoroughly analyzed.
Herein, we report a highly sensitive fluorogenic Cys probe (1) by installing the recognition moiety of 2,4-dinitrobenzenesulfonyl ester (DNBS) onto a coumarin fluorophore.
We used two standard fluorophores: Erythrosin B and Coumarin 153.
Coumarin (2H-1-benzopyran-2-one; 2H-chromen-2-one) derivatives are a large class of important naturally occurring and synthetic oxygen-containing heterocycles.
Click Chemistry in the Synthesis of Coumarin Derivatives as Dual Action HIV-1 Protease and Reverse Transcriptase Inhibitors.
This results in the formation of a big, essential planar heterocyclic ring system with 4.349[degrees] and 5.217[degrees] dihedral angle between the newly formed ether ring and the two original coumarin rings, respectively.