coxsackievirus


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Related to coxsackievirus: herpangina, Coxsackievirus B

Coxsackievirus

A large subgroup of the genus Enterovirus in the family Picornaviridae. The coxsackieviruses produce various human illnesses, including aseptic meningitis, herpangina, pleurodynia, and encephalomyocarditis of newborn infants. See Picornaviridae

Coxsackieviruses measure about 28 nanometers in diameter; they resemble other enteroviruses in many biological properties, but differ in their high pathogenicity for newborn mice. At least 23 antigenically distinct types in group A are now recognized, and 6 in group B.

After incubation for 2–9 days, during which the virus multiplies in the enteric tract, clinical manifestations appear which vary widely. Diagnosis is by isolation of virus in tissue culture or infant mice. Stools are the richest source of virus. Neutralizing and complement-fixing antibodies form during convalescence and are also useful in diagnosis. See Antibody, Complement-fixation test

The coxsackieviruses have worldwide distribution. Infections occur chiefly during summer and early fall, often in epidemic proportions. Spread of virus, like that of other enteroviruses, is associated with family contact and contacts among young children. See Animal virus, Virus classification

coxsackievirus

[ku̇k′säk·ē‚vī·rəs]
(virology)
A large subgroup of the enteroviruses in the picornavirus group including various human pathogens.
References in periodicals archive ?
Besides its antiviral effect against HRV 14 Bioaron C[R] was tested against another member of the picornaviridae, the nonenveloped plus strand RNA virus: coxsackievirus subtype A9 (CA9).
The genus enterovirus belongs to the family picornaviridae comprising 66 human serotypes that are classified into 5 groups: (i) poliovirus serotypes 1-3; (if) human enterovirus A (HEV-A), including 11 serotypes of coxsackievirus A and EV 71; (iii) human enterovirus B (HEV-B) with 38 serotypes including all coxsackievirus B, all echoviruses, EV69, EV73, and CA9; (iv) human enterovirus C (HEV-C), including 11 serotypes of coxsackievirus A; and (v) human enterovirus D (HEV-D) with only 2 serotypes--EV68 and EV70.
Selenium-deficient mice had more heart damage from the echovirus and the B1 coxsackievirus than the animals getting ample selenium.
In vitro mutational and inhibitory analysis of the cis-acting translational elements within the 5' untranslated region of coxsackievirus B3: potential targets for antiviral action of antisense oligomers.
The report presents a detailed analysis of the Coxsackievirus diagnostics market in the US, Europe, (France, Germany, Italy, Spain, UK) and Japan.
AIDS/HIV, Adenovirus, Aeromonads, Bartonella, Blastocystis Hominis, Campylobacter, Candida, Chancroid, Chlamydia, Clostridium, Coronavirus, Coxsackievirus, Cryptosporidium, Cyclospora, CMV, E.
Coxsackievirus A21, enterovirus 68, and acute respiratory tract infection, China.
Astragaloside IV attenuates myocardial fibrosis by inhibiting TGF-[beta]1 signaling in coxsackievirus B3-induced cardiomyopathy.
Coxsackievirus B1 is associated with induction of -cell autoimmunity that portends type 1 diabetes.
a-Lipoic acid attenuates coxsackievirus B3-induced ectopic calcification in heart, pancreas, and lung.
Moreover, the relatively mild cardiac damage and cTnI release in the acute phase of experimental coxsackievirus B3-induced myocarditis gives rise to cTnAAb formation (14).
Mortality in mice infected with an amyocarditic coxsackievirus and given a subacute dose of mercuric chloride.