coxsackievirus


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Related to coxsackievirus: herpangina, Coxsackievirus B

Coxsackievirus

A large subgroup of the genus Enterovirus in the family Picornaviridae. The coxsackieviruses produce various human illnesses, including aseptic meningitis, herpangina, pleurodynia, and encephalomyocarditis of newborn infants. See Picornaviridae

Coxsackieviruses measure about 28 nanometers in diameter; they resemble other enteroviruses in many biological properties, but differ in their high pathogenicity for newborn mice. At least 23 antigenically distinct types in group A are now recognized, and 6 in group B.

After incubation for 2–9 days, during which the virus multiplies in the enteric tract, clinical manifestations appear which vary widely. Diagnosis is by isolation of virus in tissue culture or infant mice. Stools are the richest source of virus. Neutralizing and complement-fixing antibodies form during convalescence and are also useful in diagnosis. See Antibody, Complement-fixation test

The coxsackieviruses have worldwide distribution. Infections occur chiefly during summer and early fall, often in epidemic proportions. Spread of virus, like that of other enteroviruses, is associated with family contact and contacts among young children. See Animal virus, Virus classification

McGraw-Hill Concise Encyclopedia of Bioscience. © 2002 by The McGraw-Hill Companies, Inc.

coxsackievirus

[ku̇k′säk·ē‚vī·rəs]
(virology)
A large subgroup of the enteroviruses in the picornavirus group including various human pathogens.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Oncolytic viruses such as the coxsackievirus could transform the way we treat cancer and could signal a move away from more established treatments such as chemotherapy," concluded Dr Nicola Annels, one of the researchers of the study.
C1v2015, enterovirus subgenogroup C1 strain discovered in 2015; CV-A, coxsackievirus genogroup A; EV-A71C1, enterovirus A71 subgenogroup C1; N, node; UTR, untranslated region; VP, viral protein.
Outbreak of hand, foot and mouth disease / herpangina associated with coxsackievirus A6 and A10 infections in 2010, France: a large citywide, prospective observational study.
"While coxsackievirus does not generally cause serious illness, it is highly contagious, passing from person to person and remaining on surfaces long enough to spread infection from shared objects and toys.
Enterovirus D68 was the most frequently reported type (56%); echovirus 30, coxsackievirus A6, echovirus 18, and coxsackievirus B3 were also frequently reported.
IgM antibodies were studied against the following viruses in the respiratory tract profile kit: RSV, adenovirus type 3, influenza virus type A (H1N1 and H3N2), influenza virus type B, parainfluenza virus types [1-4], echo virus type 7, and coxsackievirus types B1 and A7.
Sung, "Update on coxsackievirus B3 myocarditis," Current Opinion in Rheumatology, vol.
Coxsackievirus 16 and 24 were also found in 2 patients (1/62 each, 1.6%).
DeSantis, "Treatment of viral myocarditis caused by coxsackievirus B," American Journal of Health-System Pharmacy, vol.
Proteasome inhibition reduces coxsackievirus B3 replication in murine cardiomyocytes.
Bioaron C[R] inhibited the replication of human rhinovirus and coxsackievirus, both viruses belonging to the family of picornaviridae and both representing non-enveloped RNA viruses.