(2014) divided crista galli in three groups considering its relationships with cribriform
lamina of the ethmoid bone: type I--crista galli situated entirely above the lamina cribriformis, type II--crista galli situated less than 1/2 of its height under the lamina cribriformis, type III--crista galli situated more than 1/2 of its height under the lamina cribriformis.
(23) have reported preliminary evidence that advanced morphologic features, such as cribriform
, influences the visibility of prostate lesions more so than tumors of the same grade with differing architectural patterns.
It is now recognized that GP 4 in conventional acinar adenocarcinoma has 4 basic patterns: cribriform
, fused, poorly formed, and glomeruloid glands (Figure 3, A through D).
Epithelial and myoepithelial cells appear as cribriform
, tubular, and solid nests.
(e) A focus of tumor arranged in cribriform
pattern involving the subcutaneous tissue (H&E, magnification = 20 x).
In the histopathologic and immunohistochemical examinations, the case was diagnosed as granulomatous lobular mastitis and in situ ductal carcinoma (cribriform
 The three histological variants of ACC are cribriform
, tubular, and solid, although cribriform
is the most common and solid is the least common.
Importantly, the involved glands were not completely filled or distended by the foamy cells nor did they show dense or loose cribriform
or micropapillary architecture, marked nuclear atypia or comedo-type necrosis that would have suggested a diagnosis of intraductal carcinoma with foamy features.
Features previously reported to be associated with HGD diagnosis (nuclear pleomorphism, loss of nuclear polarity, architectural complexity, cribriform
glands, and/or papillary configuration) and stratification reaching more than half way of the crypt epithelium thickness  were also evaluated by the reviewers.
Metastatic carcinoma with the ductal cribriform
pattern was corroborated (Figure 2).
Microscopically, the neoplasm is composed of cohesive, uniform, cuboidal cells with minimal cytoplasm, arranged in nests and cribriform
structures of variable size and shape, separated by moderate amount of fibrotic dense stroma (Figure 1).
The tumour showed extensive cribriform
and tubular islands of malignant epithelium infiltrating hyaline stroma, containing intraluminal basement membrane like material.