The common lipid peroxides created by lipid peroxidation include malondialdehyde (MAD), 4-hydroxynonenal (HNE), crotonaldehyde
, and acrolein .
Except for ketones, crotonaldehyde
was generated for the other group of tested chemicals.
DNA interchain cross-links formed by acrolein and crotonaldehyde
The other product of dehydrogenation is acetaldehyde, which can be used as an intermediate in the production of acetic acid, acetic anhydride, ethyl acetate, butyraldehyde, crotonaldehyde
, n-butanol and many other chemicals.
The Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area documents the established maximum workplace concentrations of seven selected occupational toxicants, such as acrylonitrile, crotonaldehyde
, and trichloroethylene.
This conversion of acetaldehyde to crotonaldehyde
in the presence of spermidine and other polyamines also can occur in the mouth and throat (i.
Unsaturated aldehydes such as acrolein, crotonaldehyde
, and cinnamaldehyde are three-functional, while aliphatic diamines can be up to five-functional.
PdG has been shown to be responsible for the genotoxic and mutagenic effects of crotonaldehyde
Carbonyl content, crotonaldehyde
, and unsaturated hydrocarbons were also detected.