cryoprecipitate

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Related to cryoprecipitates: fresh frozen plasma

cryoprecipitate

[¦krī·ō·prə′sip·ə‚tāt]
(biochemistry)
The precipitate of a cryoglobulin.
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No Transfusion Yes Transfusion n=39 n=88 Piggyback LT technique (%) 2(5) 7(8) Full-size/split LT 39/0 78/10 Operative time (min) * 227 (135-320) 240 (150-420) Intraoperative RBC * 0 2(0-6) Intraoperative plasma * 6.6 (0-14) 9 (0-16) Intraoperative cryoprecipitates * 0 (0-7) 0 (0-9) Intraoperative platelets * 0 (0-8) 0 (0-15) Perioperative RBCs transfusion * 0 3.5 (1-16) PP Piggyback LT technique (%) 0.9 Full-size/split LT 0.06 Operative time (min) * 0.02 Intraoperative RBC * 0.0001 Intraoperative plasma * 0.0001 Intraoperative cryoprecipitates * 0.28 Intraoperative platelets * 0.024 Perioperative RBCs transfusion * 0.0001 * Median and range; LT: liver transplantation; RBCs: red blood cells.
There is still high variability between different centers in the use of fresh frozen plasma (FFP), platelets, cryoprecipitate, fibrinogen, antifibrinolytic drugs, or desmopressin during perioperative period to prevent surgical bleeding.
In cryoglobulinemia, a histologic examination of kidney biopsies usually reveals glomerular infiltration by activated macrophages and intraluminal microthrombi (cryoprecipitates) in vessels; immunofluorescence or electron microscopy analysis may reveal subendothelial deposits of IgM, IgG, and complement (2).
The mortality rate is 5070% despite aggressive therapy that includes intravenous fluids, antibiotics, vasopressors, steroids, heparin, packed red blood cells, platelets, cryoprecipitates, and fresh frozen plasma [5,6].
Determination of di-2-ethylhexyl phthalate levels in human blood plasma and cryoprecipitates. Environmental Health Perspectives, 3, 119-121.
In the present study, this lower extraction efficiency might be attributable to cryoprecipitates in the plasma.
After serum separation, most laboratories (66%) allowed the sample to cryoprecipitate at different temperatures.