and toxoplasma encephalitis in an AIDS patient.
It has been reported that some of the antiretrovirals used in the HAART regime interact with antifungal agents used to treat cryptococcosis and HIV patients with cryptococcal meningitis
who initiate antiretroviral therapy are at particularly high risk for the immuno-reconstitution inflammatory syndrome (IRIS) (4).
In the 3 cases described here, the specific conditions the treatment teams failed to identify as indicators of HIV infection were thrombocytopenia, pneumocystis pneumonia, herpes zoster, and cryptococcal meningitis
Chuang, "The prognostic factors of cryptococcal meningitis
in HIV-negative patients," Journal of Hospital Infection, vol.
These findings are highly suggestive of cryptococcal meningitis
Treatment of cryptococcal meningitis
in KwaZulu-Natal, South Africa.
 Altered sensorium was found in 55%, 14 cases of CNS Tuberculosis, 4 cases of Cryptococcal meningitis
, & 2 cases of pyogenic meningitis.
Mylonakis, "Epidemiology and management of cryptococcal meningitis
: developments and challenges," Expert Opinion on Pharmacotherapy, vol.
The key to reducing the mortality from Cryptococcal meningitis
, which is a consequent of crag positivity, is early diagnosis of crag in ART-naive AIDS patients prior to initiation of ART therapy and the integration of both ART therapy and primary prophylaxis with Fluconazole; this has been shown to reduce mortality from Cryptococcal meningitis
consequent of crag positivity even at CD4 cell count within the range of <100 cells/[micro]l.
His system, now taken up by researchers in the United States and Europe, has been adapted to the study of other diseases of the brain such as viral encephalitis, tumour metastasis, multiple sclerosis and cryptococcal meningitis
. J Neurol Neurosurg Psychiatry 1985; 48:853-858.