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Related to cryptococcosis: histoplasmosis


see fungal infectionfungal infection,
infection caused by a fungus (see Fungi), some affecting animals, others plants. Fungal Infections of Human and Animals

Many fungal infections, or mycoses, of humans and animals affect only the outer layers of skin, and although they are sometimes
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(European blastomycosis), a deep-systemic fungal disease of man and animals caused by the yeastlike fungus Cryptococcus neoformans.

Cryptococcosis is a rare and serious disease, found in all countries. The sources of infection for man and the paths of dissemination of the pathogenic principle are unknown.

In man, cryptococcosis is characterized by predominant affection of the lungs, central nervous system, skin, and subcutaneous tissue, with subsequent metastases to the viscera. Diagnosis of the disease is difficult; laboratory diagnosis consists in isolation of the causative agent. The disease is treated medicinally (amphotericin B), combined with anticryptococcal rabbit serum or gamma globulin.

In animals, cryptococcosis is widespread in the USA, Denmark, Italy, France, and the Netherlands, and it has been recorded in Switzerland and the USSR. Cattle, cats, dogs, and monkeys are affected. The causative agent enters the animal’s body through the respiratory and digestive tracts. In cattle, cryptococcosis produces alternate chills and fever, swelling and soreness in the udders, a sharp decrease in milk production, and, with metastasis to the lungs, pneumonia. In dogs and cats, it affects the lungs and central nervous system. The diseased animals show disturbances of coordination, labored breathing, cough, and, occasionally, blindness. Treatment has not been developed. Zoo-hygienic and sanitary measures are of decisive importance in preventing cryptococcosis in animals.


Spesivtseva, N. A. Mikozy i mikotoksikozy, 2nd ed. Moscow, 1964.


A yeast infection of humans, primarily of the central nervous system, caused by Cryptococcus neoformans. Also known as torulosis.
References in periodicals archive ?
The first reported case of cutaneous cryptococcosis in a patient with underlying lupus involved a 24-year-old woman who presented with cellulitis of the thigh and gluteus and who went on to develop nephrotic syndrome, arterial hypertension, and ultimately fatal acute renal insufficiency (Mycoses 2001; 44:419-21).
Milestones in the history of Cryptococcus and cryptococcosis.
The discovery of very rare viral inclusion bodies within the renal tubular epithelium had initially raised speculation about an underlying viral infection as a possible predisposing condition for disseminated cryptococcosis.
One patient had abnormal findings on chest radiography that were attributed to cryptococcosis.
20pm Once again cryptococcosis is raising its ugly head, as Jordan has to make a tough decision - should he reveal Robert's involvement in the outbreak, or keep it under his hat?
The radiological findings of cryptococcosis also depend on the immune status of the patient.
KEY WORDS: British Columbia, cryptococcal disease, cryptococcosis, Cryptococcus gattii, ecological niche modeling, fungal disease, GARP, Genetic Algorithm for Rule-set Prediction, geographic information systems, GIS.
Background & objectives: Cryptococcosis is a chronic infective condition affecting the central nervous system.