curare


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Related to curare: atropine

curare

(kyo͝orär`ē), any of a variety of substances originally used as arrow poisons by Native South Americans in hunting and in warfare. The main active substance of curare, tubocurarine, is an alkaloid extracted from Chondodendron tomentosum, Strychnos toxifera, and other plant species. The poison produces muscle paralysis by interfering with the transmission of nerve impulses at the receptor sites of all skeletal muscle. Muscles with many nerves, such as eye muscles, are affected first. In recent years curare has been put to medical use. When given in small quantities with general anesthesiaanesthesia
[Gr.,=insensibility], loss of sensation, especially that of pain, induced by drugs, especially as a means of facilitating safe surgical procedures. Early modern medical anesthesia dates to experiments with nitrous oxide (laughing gas) by Sir Humphry Davy of England
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, especially in abdominal surgery, curare ensures the desired relaxation of muscle tissue with a minimal concentration of the anesthetic, lessening the possibilities of anesthesia-induced complications. Curare is also used to relieve spastic paralysis, to treat some mental disorders, and to induce muscle relaxation for the setting of fractures.

Curare

 

(from Carib kurari), a mixture of condensed extracts from plants of the genera Strychnos, Chondodendron, and other South American groups.

Upon entering the blood, curare blocks the transmission of neural impulses from the motor nerves to the skeletal musculature, causing muscular relaxation. Curare was used for centuries by natives of South America as an arrow poison. It contains a large number of alkaloids of the curarine group. Curariform agents are used for therapeutic purposes.

curare

[kyü′rä·rē]
(organic chemistry)
Poisonous extract from the plant Strychnos toxifera containing a mixture of alkaloids that produce paralysis of the voluntary muscles by acting on synaptic junctions; used as an adjunct to anesthesia in surgery.

curare

, curari
1. black resin obtained from certain tropical South American trees, esp Chondrodendron tomentosum, acting on the motor nerves to cause muscular paralysis: used medicinally as a muscle relaxant and by South American Indians as an arrow poison
2. any of various trees of the genera Chondrodendron (family Menispermaceae) and Strychnos (family Loganiaceae) from which this resin is obtained
References in periodicals archive ?
There are many drugs that, like curare, compete with natural agonists for receptors.
Era una cosa completamente inusuale, per quei tempi ed in certe zone, vedere una donna medico, ma probabilmente fu proprio il suo essere donna che le permise di curare donne beduine ed arabe musulmane che mai erano state curate prima di allora da un medico.
Bennett introduced curare into clinical practice in 1940 in convulsive therapy practice in order to prevent injuries from unmodified seizures that had been induced with metrazol (pentamethylenetetrazol) (4).
Among other places her work has been published in Word Thursdays Anthology, Curare, and Breukelen Magazine, and performed on Let's Dine Like Jack Johnson Tonight, a CD by The No Chance Ensemble, of which she is a member and director.
Del resto il misero riconoscimento economico impedisce a chi vive di traduzione di dedicarsi alla ricerca e quindi curare la qualita della propria traduzione.
From which continent is the poison curare, a source of useful medicines?
Erne demonstrated how to move silently through the jungle, make sounds for attracting animals such as caimans (crocodiles) and toucans, and use the 8-foot blowgun to paralyze monkeys or birds with curare (used in our Held as a homeopathic medicine for paralysis) so that they could be captured for food.
Tenuto conto della qualita e dell'originalita delle proposte culturali presenti, la rivista dovrebbe curare l'aspetto estetico e promozionale, e fare ulteriori sforzi per ottenere maggiore visibilita, sia migliorando la veste grafica, sia cercando una piu capillare divulgazione fra gli italianisti del Nord America e dell'Europa.
Affleck," an adaptation of Ibsen's "Little Eyolf." Melly Still, meanwhile, will follow up "Curare Boy" by directing Rory Kinnear in the Jacobean classic "The Revenger's Tragedy."