The histological analysis of the healing skin was performed in sections stained by hematoxylin and eosin to assess re-epithelialization, acute inflammation, neo-angiogenesis, cutaneous appendages regeneration and fibroblasts proliferation.
Control subjects showed low signals of fibroblastic activity, collagen fibers, neoangiogenesis and cutaneous appendages. However, in the LG and MG the amount of granulation, collagen deposition tissue and neoangiogenesis was moderate.
Significant difference was observed between the treated and control groups, with an increase in production of fibroblasts (p = 0.0005), collagen (p = 0.0110), neoangiogenesis (p = 0.0099) and cutaneous appendages (p = 0.0008) (Table 2).
When MG and LG were compared using Dunn's Multiple Comparison Test, both therapies showed improvement in the repair of burns, with no difference between them, except the regeneration and the formation of new cutaneous appendages (p < 0.01), observed in microcurrent therapy (Table 3).
CD10 may be useful for the differential diagnosis between benign tumors of cutaneous appendages originating from the hair follicle and BCC as an immunohistochemical marker and it may solve a dilemma for the clinician and the pathologist, particularly in small and superficial biopsies.
One study reported the usefulness of CD10 for differential diagnosis between benign tumors of cutaneous appendages originating from the hair follicle and BCC as an immunohistochemical marker, especially in the small and superficial biopsies.
(11) Elsewhere in the literature, one study retrieved 30 cases of benign tumors of cutaneous appendages originating from the hair follicle and 30 cases of BCC.