O'Brien cited as one example a Harvard University study of 28 patients exhibiting migraine with the associated cutaneous pain
and tenderness known as allodynia.
Gradual increase in cutaneous pain
threshold was found in healthy subjects and patients with atopic eczema during repeated hypnotic sessions with specific suggestions.
Contribution of neurokinin 1 receptors in the cutaneous orofacial cutaneous pain
Yang Bo, at Zhejiang University, China, demonstrated a dose dependant analgesic effect of ETI-211 that persisted for up to 72 hours when injected subdermally in a guinea pig model of cutaneous pain
Somatic nociceptors, found in blood vessels, ligaments, and bones, have a low concentration of nerve endings, yielding dull, more diffuse pain that typically lasts longer than cutaneous pain