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Related to cyclic guanosine monophosphate: Cyclic adenosine monophosphate


C10H13O5N5 Guanine riboside, a nucleoside composed of guanine and ribose. Also known as vernine.



the nucleoside consisting of the carbohydrate ribose and the nitrogen base guanine. Colorless crystals. Molecular weight, 283.26 and melting point. 235° C. Free guanosine is an intermediate product of metabolism. It is a component of nucleic acids and biologically active guanyl nucleotides, GMP, GDP. and GTP. GTP (guanosine triphosphate), an energy-rich phosphorus compound, is a coenzyme of some reactions, such as the amination of inosinic acid and the transference of amino acids to ribosomes during the biosynthesis of protein.

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The present findings unequivocally reveal that the intracellular signaling cascade by cyclic guanosine monophosphate (cGMP) participates in pigment aggregation in the red ovarian chromatophores of Macrobrachium olfersi.
Also, the substances nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) are incorrectly described as having separate effects on smooth muscle cells (pages 26 and 104, table 11.
Nitric oxide then activates the enzyme guanylate cyclase which causes increased levels of cyclic guanosine monophosphate (cGMP), which produces smooth muscle relaxation in the corpus cavernosum and allows for an inflow of blood resulting in an erection.
Linaclotide-induced intestinal pain reduction is thought to result from an increase in cyclic guanosine monophosphate (cGMP), which has been shown to decrease the activity of pain-sensing nerves.
In a similar manner, cyclic guanosine monophosphate (cGMP), as a measure of NO activities, is almost 10 times increased in cardiomyocytes after the stimulation either by bradykinin, in contrast to previous studies [10], or by acetylcholine [12].
This nonspecific vasodilator agent blocks the distribution of cyclic nucleotides such as cyclic adenosine monophosphate and cyclic guanosine monophosphate and causes vasodilatation by inhibition of phosphodiesterase.

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