cyclizine hydrochloride


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cyclizine hydrochloride

[′sī·klə‚zēn ‚hī·drə′klȯr‚īd]
(pharmacology)
(C6H5)2CHC4H8N2CH3·HCl A white, crystalline powder with a melting point of 285°C; used in medicine.
References in periodicals archive ?
Various amounts of diverse interfering compounds were added to a fixed amount of cyclizine hydrochloride (1 mg/mL) and the recommended procedure for the spectrophotometric determination was followed.
Applications ] The proposed method is successfully applied for the quality control of pure cyclizine hydrochloride and in the pharmaceutical dosage form as shown in Table-4.
Standard solution (w/v) (1.0 mg/mL) of cyclizine hydrochloride (GlaxoSmithKline, 35-Dockyard Road.
To an aliquot of cyclizine hydrochloride containing 50ug to 200ug/mL was added 1.5 mL of 2 M sodium hydroxide, 2.0 mL of 2 % (w/v) m- dinitrobenzene and the contents were heated for 80 seconds in a water bath at 100degC, cool and the volume was made upto 10 mL with ethyl alcohol.
Table-4: Determination of cyclizine hydrochloride in pharmaceutical preparations.
7: Standard calibration curve of cyclizine hydrochloride.
Procedure for Studying the Interfering Compounds To an aliquot containing 1.0 mg/mL of cyclizine hydrochloride different amounts of various compounds (1 mg/mL) were added individually until the solution showed the same (+0.01) absorbance as that of pure cyclizine hydrochloride solution without the addition of the organic compound, under experimental conditions, as described in the general procedure.
Procedure for Determination of Cyclizine Hydrochloride in Pharmaceutical Preparations
Tablets containing l0mg cyclizine hydrochloride were powdered, weighed, dissolved in water and filtered.