cycloheximide


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cycloheximide

[¦sī·klō′hek·sə‚mīd]
(microbiology)
C15H23NO4 Colorless crystals with a melting point of 119.5-121°C; soluble in water, in amyl acetate, and in common organic solvents such as ether, acetone, and chloroform; used as an agricultural fungicide.
References in periodicals archive ?
mice and subjected to the apoptosis inducers cycloheximide [35] orpuromycin [36], respectively, to validate our experimental model.
Seven strains were isolated with paraffin baiting technique as compared with Sabouraud dextrose agar, Sabouraud dextrose agar with cycloheximide and paraffin agar (Table 1).
There was no clear evidence of any differences as a result of using (a) cycloheximide vs puromycin treatment for NMD inhibition; (b) differing RNA extraction methods; (c) oligo d(T) and random hexamers vs gene specific primers; (e) various methods of DNase treatment; and (f) a particular type or brand of Taq polymerase.
P Highfield, "Inhibition of DNA synthesis in synchronized Chinese hamster cells treated in G1 with cycloheximide," Experimental Cell Research, vol.
Inclusion of alpha-bungarotoxin, a nicotinic acetylcholine receptor antagonist, or cycloheximide, a protein synthesis inhibitor, during nicotine treatment abolished nicotine-induced podosome rosette formation in the rat cells, suggesting that signalling through the nicotinic acetylcholine receptors and synthesis of new proteins are required for podosome rosette formation.
In addition to these effects, NAC treatment elicited a dose- and time-dependent increase in the Cyr61 expression that was accompanied by an increase in its mRNA and blocked by cycloheximide pretreatment.
For the culture, samples were inoculated in two types of Sabouraud's dextrose agar (SDA) culture media; one was SDA with the addition of chloramphenicol and gentamicin to inhibit the growth of bacteria, and the second was SDA containing chloram-phenicol and cycloheximide (Mycosel agar) to inhibit the growth of saprophytic fungi.
All specimens were inoculated into Sabouraud's dextrose agar (plain), Sabouraud's dextrose agar with antibiotic, Sabouraud's dextrose agar with antibiotic and 5 Percent cycloheximide.
trachomatis in cycloheximide treated McCoy cell monolayer, which was grown on cover slip cultures in 12-well plates using RPMI supplement with 10% fetal bovine serum (FBS), 2 mM L-glutamine and antibiotics.
Extracts of Angelica sinensis ameliorate scopolamine and cycloheximide, but not p-chloroamphetamine-induced amnesia at 1 g/kg b/w in animal studies.