cystic fibrosis transmembrane conductance regulator


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Related to cystic fibrosis transmembrane conductance regulator: CFTR

cystic fibrosis transmembrane conductance regulator

[¦sis·tik fī¦brō·səs tranz¦mem‚brān kən′dək·təns ‚reg·yə‚lād·ər]
(cell and molecular biology)
A specialized chloride channel that is regulated by cyclic adenosine monophosphate; its disruption has been implicated in cystic fibrosis.
References in periodicals archive ?
Cystic fibrosis transmembrane conductance regulator dysfunction alters physiological functions of both surface and submucosal gland of epithelium, which leads to salt and water imbalance across airway epithelium, depleted surface liquid layer, and impaired MCC.
Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor Nat Genet 1996;12:280-7.
The international, multi-centre, double-blind, randomised, multi-dose, placebo-control trial will concentrate on assessing Resunab's safety and tolerability in up to 70 adults with cystic fibrosis regardless of their cystic fibrosis transmembrane conductance regulator mutation.
A cluster of highly polymorphic dinucleotide repeats in intron 17b of the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
According to PTI, recent research demonstrates that CF is a disease characterised by improper folding and inadequate trafficking of the cystic fibrosis transmembrane conductance regulator (CFTR) protein.
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