2 Gy (100 or 200 mGy) of x-rays results largely from stimulation of the cytocidal
activity of macrophages that secrete increased amounts of nitric oxide.
Presently, it is considered that the anticancer effects of fungal polysaccharides arise from the activation of the body's immune system rather than direct cytocidal
effects (Zhou et al.
The anticancer effect of Astragalus polysaccharide is most likely due to its immunomodulatory effect rather than direct cytocidal
action [23, 24].
effect of Streptococcus pyogenes on mouse neutrophils in vivo and the critical role of streptolysin S.
First, we confirmed the cytocidal
effect of hypotonic shock induced by sterile water on bladder cancer cells.
This effect was concentration dependent, and the extracts had cytotoxic and cytocidal
PGL-I has been shown to play an important role in downregulating the inflammatory immune response, inhibits dendritic cell maturation and activation, facilitates entry of bacilli into macrophages and SCs, and scavenges potentially cytocidal
oxygen metabolites in vitro, all of which would promote the survival of intracellular bacilli.
Potent membrane-permeabilizing and cytocidal
action of Vibrio cholerae cytolysin on human intestinal cells.
and immunopotentiating effects of relatively low molecular weight products derived from the basidiomycete, Agaricus blazei Murrill.
ATP assay: ability to distinguish cytostatic from cytocidal
anticancer drug effects".
A Bacillus thuringiensis Crystal Protein with Selective Cytocidal
Action to Human Cells.
24) Neopterin is formed preferentially in response to Th1-type cytokine interferon-[gamma], and, because of its ability to amplify deleterious effects of radicals in various cellular systems, neopterin seems part of the pro-inflammatory and cytocidal
armature of the activated human macrophage.