A Bacillus thuringiensis crystal protein with selective cytocidal
action to human cells.
Overexpression and Cytocidal
Activity of Parasporin-1 from Bacillus thuringiensis against Human Cancer Cell Lines.
Hypokalemia is easily manageable with appropriate monitoring and is less critical than the AEs associated with cytocidal
therapies, yet serious hypokalemia often provokes arrhythmia, flaccid paralysis, and respiratory depression, which are life-threatening complications that require urgent treatment.
Hirotsu et al., "The cytocidal
activity of OK-432-activated mononuclear cells against human glioma cells is partly mediated through the Fas ligand/Fas system," Japanese Journal of Cancer Research, vol.
The same research group also demonstrated in another study (82) that inhibition of the tumor metastases by single exposure of mice to 0.1 or 0.2 Gy (100 or 200 mGy) of x-rays results largely from stimulation of the cytocidal
activity of macrophages that secrete increased amounts of nitric oxide.
Roberts et al., "Microbicidal properties and cytocidal
selectivity of rhesus macaque theta defensins," Antimicrobial Agents and Chemotherapy, vol.
Evaluation of the proliferation of cells is a noteworthy step since most of anticancer drugs are less cytocidal
to quiescent cells than to actively proliferating cells .
Presently, it is considered that the anticancer effects of fungal polysaccharides arise from the activation of the body's immune system rather than direct cytocidal
effects (Zhou et al., 2007), and the molecular mechanism of Cordyceps polysaccharides against cancer metastasis is unknown.
The anticancer effect of Astragalus polysaccharide is most likely due to its immunomodulatory effect rather than direct cytocidal
action [23, 24].
effect of Streptococcus pyogenes on mouse neutrophils in vivo and the critical role of streptolysin S.
A cytostatic effect (TGI) was observed when T [greater than or equal to] To, and a cytocidal
effect ([LC.sub.50]) was observed when T<To.
First, we confirmed the cytocidal
effect of hypotonic shock induced by sterile water on bladder cancer cells.