cytokine receptor


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cytokine receptor

[′sīd·ə‚kīn ri‚sep·tər]
(cell and molecular biology)
A type of cell-surface receptor that binds to cytokines, initiating the Jak-STAT signaling pathway within the cell.
References in periodicals archive ?
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
In the acute phase of mental illness, elevations have been found in both interleukin-6 (IL-6) and the cytokine receptor soluble IL-2 (SIL-2R); for MDD and schizophrenia, cytokine levels are acutely increased, tend to decrease with treatment, and eventually rise again, he said.
Cases have been reported of [gamma]c receptor signaling deficiencies with subtle manipulations of the in vitro systems to determine the specific cytokine receptor defect.
Levels of cytokine receptor activator of nuclear factor kappa B ligand in gingival crevicular fluid in untreated chronic periodontitis patients.
There are indications that polymorphisms in cytokine and cytokine receptor genes could influence genetic disease resistance and susceptibility (Atac et al.
Seattle, WA) has patented novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor.
10) Most patients with CMC, however, show normal cytokine receptor expression for both IFN[gamma] and IL-12 receptors.
For example, the receptors for six different members of a group of cytokines called interleukins contain a protein called the cytokine receptor gamma chain.
The gene codes for the gamma-c chain sub-unit of the interleukin-12 cytokine receptor, which is defective in the disease.
The method includes the steps of immunizing an animal with a cytokine receptor or portion of a cytokine containing the critical binding site which portion includes the extracellular domain 4 or analogous domain in the analogous common receptor or part thereof.
Early development and tissue growth/renewal: wingless-Int, tumor growth factor-[beta], hedgehog, receptor tyrosine kinases, notch-delta, cytokine receptor (STAT)
Poland, all of Mayo Clinic, authored the study Associations between Single Nucleotide Polymorphisms and Haplotypes in Cytokine and Cytokine Receptor Genes and Immunity to Measles Vaccination.