cytomegalovirus


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Related to cytomegalovirus: Cytomegalovirus infection, Epstein Barr virus

cytomegalovirus

(sī'təmĕg'əlōvī`rəs), member of the herpesvirus family that can cause serious complications in persons with weakened immune systems and infants. A common virus, it is estimated that up to 80% of Americans carry cytomegalovirus by the time they reach adulthood. Most experience no symptoms or mild symptoms such as enlarged lymph nodes, low fever, and fatigue that may or may not be noticed. Cytomegalovirus is present in body fluids (saliva, semen, cervical secretions, and urine) and can be spread from person to person by sexual contact, kissing, or the sharing of food. It can also be transmitted from mother to fetus. The virus usually remains dormant in the body, but it can reactivate and cause serious symptoms in immunologically suppressed patients, such as those with AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
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, or in infants whose immune systems are not yet fully developed. An estimated 25% of AIDS patients experience CMV infection, often in the form of a viral retinitis that can lead to blindness. Infants can become infected before birth when the mother becomes infected or experiences a recurrence during pregnancy. In a newborn, CMV can be life-threatening, and it can lead to later complications such as cerebral palsy, blindness, hearing problems, mental retardation, and learning disabilities. The antiviral drugs foscarnet and ganciclovir are used to keep active infections under control.

cytomegalovirus

[¦sīd·ō¦meg·ə·lō′vī·rəs]
(virology)
An animal virus belonging to subgroup B of the herpesvirus group; causes cytomegalic inclusion disease and pneumonia.
References in periodicals archive ?
Cytomegalovirus immunoglobulin, either alone or in combination with antiviral medications, is not currently indicated for the treatment of CMV colitis.
The report reviews key players involved Cytomegalovirus (HHV-5) Infections therapeutics and enlists all their major and minor projects
Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection.
Meylan, "Treatment of cytomegalovirus infection or disease in solid organ transplant recipients with valganciclovir," Transplantation Proceedings, vol.
Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review.
Research shows that about 60 to 90% of adults harbor a virus called cytomegalovirus (CMV), which depletes naive immune cells.
Identify and understand important and diverse types of therapeutics under development for Cytomegalovirus (HHV-5) Infections.
Key topics covered include strategic competitor assessment, market characterization, unmet needs and the implications for the Cytomegalovirus (CMV) Infections Therapeutics market.
She said blindness in immune-compromised people, such as HIV-patients, is most commonly caused by a viral infection called cytomegalovirus, which normally thrives on a weakened immune system.
The test is traceable to the first World Health Organization (WHO) International Standard for Human Cytomegalovirus for Nucleic Acid Amplification Techniques and reliably monitors cytomegalovirus (CMV) infections.

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