cytopenia


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cytopenia

[‚sīd·ō′pē·nē·ə]
(pathology)
A blood cell count below normal.
References in periodicals archive ?
Ten samples were assigned to 2 tracks, which included the cytopenia track and 1 other track.
Clinical significance of somatic mutation in unexplained blood cytopenia. Blood 2017;129:3371-8.
(1,4) According to the HLH-2004 diagnostic and therapeutic guidelines for HLH, the diagnosis is made by the presence of five of the following eight criteria: fever, splenomegaly, cytopenia, hypertriglyceridemia or hypofibrinogenemia, hemophagocytosis, low natural killer cell activity, elevated ferritin, and elevated soluble interleukin-2 levels.
Myelodysplastic morphology of blood cells can be encountered not only in myelodysplastic syndromes but also can be seen in non-clonal disorders, cause of which can be pointed to viral, bacterial, parasitic infections, autoimmune disorders, juvenile rheumatoid arthritis, immune thrombocytopenic purpura, iron deficiency anemia, megaloblastic anemia, dysgranulopietic neutropenia, congenital neutropenia, malignant lymphoma, after administration of granulocyte colony stimulating factor, chemotherapy, steroids, smoking, alcohol, posttransplantation, copper deficiency also, together with or without cytopenia. (Olcay, 2016)
(5) Moreover, studies have shown that bone marrow involvement is more likely to occur in patients with multisystem involvement resulting in cytopenia. (5) Our patient had bilateral temporal bone involvement and hard palate involvement.
Laboratory test results pointing to this kind of disease--lactate dehydrogenase (LDH), beta 2 microglobulin, high sedimentation rate, pathological ratio of serum immunoglobulins and proteins and cytopenia, were absent.
Other inexpensive and informative biomarkers of potential body burden and inflammatory or suppressive effects are hs-CPR and CBC assessing for cytopenia. (89)
http://www.uptodate.com/contents/approach-to-the-adult-with-unexplained-thrombo cytopenia (Accessed October 2016).
Cytopenia (in at least two of the three cell lineages)
Such treatment has the potential for improving cytopenia and the symptoms of splenomegaly [11].
There may be associated morphological abnormalities (short stature, broad nasal bridge, micrognathia), ophthalmological abnormalities (chronic corneal inflammation), and haematological disorders (episodic cytopenia) [10-12].
Myelodysplastic syndrome (MDS) is a heterogeneous group of diseases, caused by clonal stem cell disorders, with the specific sign of peripheral cytopenia due to ineffective hemopoiesis with normal or increased cellularity of the bone marrow.