cytophilic antibody

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Related to cytophilic: eosinophil, anaphylaxis, cytotropic antibody

cytophilic antibody

[¦sid·ə¦fil·ik ′ant·i‚bäd·ē]
(immunology)
A substance capable of combining directly with the receptors of a corresponding antigenic cell. Also known as cytotropic antibody.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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They describe how research on the surface structure of natural scabs served as inspiration for developing a "cytophilic" wound dressing material.
Alifrangis et al., "Cytophilic antibodies to Plasmodium falciparum Glutamate Rich Protein are associated with malaria protection in an area of holoendemic transmission," Malaria Journal, vol.
They were also positive to the cytophilic IgG1 and IgG3 and negative to the non-cytophilic IgG2 and IgG4.
It is generally agreed that cytophilic IgG1 and IgG3 isotypes participate in specific protective immunity, whereas IgG2/IgG4 isotypes block its effect [16].