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According to EnGeneIC, the second-generation EDV nanocells deliver an extremely cytotoxic nemorubicin derivative (D682) directly to solid tumors via EGFR targeting on the tumor cell surface, keeping healthy tissue protected from damage.
Hexane, chloroform, ethyl acetate, methanol and aqueous extracts of the plants were evaluated for cytotoxic potential [17, 18].
Human cancer cell lines were used to evaluate the cytotoxic effect of different plant extracts.
The cytotoxic activity was studied against the MCF-7 tumour cell line using the colourimetric methyl tetrazolium (MTT) test as described by Mosmann [12] and modified in our laboratory [13].
We have shown that in a complex with the major heat shock protein Hsp70, it has a direct cytotoxic effect on some tumor cell lines [21].
Key words: Cardia obaliqua, Methanolic extract, Cytotoxic activity, Antioxidant activity, Antimicrobial activity.
Later, we examined the cytotoxic effects of CpG ODN on MCF-7 cells cultured in these two groups of media.
Unconditional criteria and conditional criteria with respect to the 4 classes of cytotoxicity were defined (the absence of cytotoxic effect, low cytotoxic effect, medium cytotoxic effect and high cytotoxic effect).
The title should be corrected to "Epstein-Barr Virus-Induced Gene 3 (EBI3) Blocking Leads to Induction of Antitumor Cytotoxic T Lymphocyte Response and Suppression of Tumor Growth in Colorectal Cancer by Bidirectional Reciprocal-Regulation STAT3 Signaling Pathway."
However, despite the evidence that single ingredients of oral rinses are cytotoxic and effective against bacteria, the impact of the complex cocktail of supplements on oral cell cytotoxicity and antimicrobial activity is largely unknown.
canadensis have been demonstrated to exert several biological activities such as cytotoxic, antifungal, antibacterial, antiviral, anti-inflammatory, antioxidant, and antiagregant (26-33).