Db, decidua basalis
; Fv, fourth ventricle; Fl, forelimb; Hl, hind limb bud; L, Labyrinth; Li, liver; Lu, lung bud; N, Nose snout projection; Tv third ventricle; T, tongue.
Alsaad et al., "Phenotypic and functional characterization of mesenchymal stem/multipotent stromal cells from decidua basalis
of human term placenta," Stem Cells International, vol.
We performed a study to isolate MSCs residing in the human placental decidua basalis
(PDB-MSCs) Wharton's Jelly (WJ-MSCs) amniotic membrane (AM-MSCs) and characterize in reference to their morphology surface phenotypes and differentiation potential in vitro in order to obtain an alternative source of MSC for BM-MSC for therapeutic clinical applications.
Invasive placental implantation occurs when there is a defect or absence of the decidua basalis
, which is replaced by loose connective tissue.
Here for the first time, the bio-characteristics of stem cells derived from human bone marrow, placenta decidua basalis
, and urine were investigated, specifically cell morphology, proliferation, phenotype, and multilineage differentiation properties.
(21,38-44) Clusters of multinucleate giant cells in the decidua basalis
and excessive numbers of extravillous trophoblasts are less commonly seen in this than in other patterns of diffuse hypoxic placental injury, (21) most likely because of the association of PR with deep trophoblastic, myometrial invasion, which was proven, at least in maternal anemia.
As a consequence of partial or total absence of decidua basalis
and imperfect development of the fibrinoid layer, placental villi are attached to the myometrium in placenta accreta, actually invade the myometrium in increta, or penetrate the myometrium in placenta percreta.
Adherent placenta is characterised by abnormal attachment of placental villi directly to myometrium due to scanty or absence of decidua basalis
and imperfect development of fibrinoid on Nitabuch layer.
Depending on whether the decidua is in contact with the site of implantation or with the fetal membranes is referred to as the decidua basalis
or decidua parietalis, respectively.
Morbid adherence of the placenta is the abnormal adherence in whole or in part of the placenta to the underlying uterine wall, due to the complete or partial absence of the decidua basalis
, in particular of its deep or spongy layer5, so that the physiological line of cleavage through the decidual spongy layer is lacking.
(11,13,14) Recently, a lesion of leukocytoclastic necrosis of the decidua basalis
, histologically similar to LN and similar to LN associated with preeclampsia, preterm birth, and decreased fetal growth, was described, but this lesion involved the maternal floor.
G.--Genome multiplication in the tertiary giant trophoblast cells in the course of their endovascular and interstitial invasion into rat placenta decidua basalis
. Early Pregman Biol.