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The deterioration of existing defense mechanisms, leading to an exacerbation of pathologic behavior.



disturbance of the activity of an organ, a system of organs, or the entire organism, as a result of exhaustion or disruption of its adaptive mechanisms.

Harmful influences that cause significant changes in the organism disturb the constant equilibrium between the organism and the external environment. After some time, the organism adapts itself to the new conditions of existence (for example, the heart muscle hypertrophies when there are heart defects) and equilibrium is restored—that is, compensation occurs. When there is compensation, the organ (or system) works under an increased load, as a result of which it succumbs more readily to harmful influences.

References in periodicals archive ?
Resuscitation and stabilization equipment should be readily available in the event that the patient decompensates and needs to be stabilized or moved to another facility.
Long-standing near exophoria which starts to decompensate during school examinations
If the dissociated heterophoria is excessive and/or if the sensory and motor fusion are inadequate then heterophoria may decompensate, in which case the patient is likely to suffer from symptoms (9) and decreased visual performance.