Decompensation


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Related to Decompensation: cardiac decompensation

decompensation

[dē‚käm·pən′sā·shən]
(psychology)
The deterioration of existing defense mechanisms, leading to an exacerbation of pathologic behavior.

Decompensation

 

disturbance of the activity of an organ, a system of organs, or the entire organism, as a result of exhaustion or disruption of its adaptive mechanisms.

Harmful influences that cause significant changes in the organism disturb the constant equilibrium between the organism and the external environment. After some time, the organism adapts itself to the new conditions of existence (for example, the heart muscle hypertrophies when there are heart defects) and equilibrium is restored—that is, compensation occurs. When there is compensation, the organ (or system) works under an increased load, as a result of which it succumbs more readily to harmful influences.

References in periodicals archive ?
The prognosis is reserved, taking into account the possibility of decompensation of all related comorbidities, the appearance of hemodynamic instability, the aggravation of vascular and parenchymatous decompensation of the liver cirrhosis, with the development of encephalopathy phenomena and evolution towards exitus.
A total of 241 patients admitted to cardiology department with decompensation of heart failure were included in the study.
The TRANSITION trial will compare administration of Entresto in hospitals and its administration after discharge from hospital in heart failure patients with decreased ejection fraction (HFrEF) who were hospitalised recently following acute decompensation. The study is expected to complete in 2018.
Of the 7 patients in our study who were left aphakic after IOL explantation due to corneal decompensation and edema, 3 were scheduled for keratoplasty, while the other 4 patients were unwilling to face the risks associated with keratoplasty because of their advanced age and good vision in the fellow eye.
Despite concerns that preterm infants with bronchopulmonary dysplasia (BPD) are more likely to experience respiratory decompensation after immunization than those without BPD, no difference in the incidence of respiratory decompensation within 72 hours after immunization was found between these groups in a cohort study at a tertiary care facility, according to a report published in Pediatrics.
Metabolic stroke can sometimes occur in the absence of acute metabolic decompensation, so meticulous neurological examination at each visit is useful.
[36] episode Mood cessation ED decompensation cessation Cerimele et al.
Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis.
They noted that family members and friends may not be privy to this information, and the patients themselves may not be in a position to answer because of decompensation with encephalopathy.
(12) However, successfully reducing medication burden can be a challenge, particularly when there is fear of decompensation or if the patient is psychologically attached to the complex medication regimen.
"The use of statins was associated with a reduced risk of decompensation and death in patients with alcoholic cirrhosis and the association between use of statins and death was more pronounced in patients with cirrhosis compared with noncirrhotic controls," the investigators noted.