be responsible for mediating its [curcumin's] beneficial effects." (14) In their research, both curcumin and vanillin acted similarly protecting against advanced glycation end products (AGEs); and they wrote that their "novel findings not only suggest that the main health benefits observed for curcumin can be ascribed to its degradation product
vanillin, but also open new avenues for developing therapeutic applications of curcumin degradation products
On the other hand, it was suggested that nano-HA could mitigate the acidity of the degradation product
due to the basic nature of its metabolites ; therefore, it can reduce tissue inflammation.
The Swedish Chemicals Agency has not found any residues of the pesticide glyphosate or its degradation product
AMPA in the products analyzed.
However, degradation product
, ALB-SX, remains in significant concentration after 120 minutes.
High concentrations of muconic acid - a degradation product
of benzene (a volatile, toxic and carcinogenic compound) - were detected in the urine of 29 pregnant women who participated in the pilot study.
As per the regulatory guidelines [3, 20], the qualification of impurities is defined as the process of acquiring and evaluating data that establishes the biological safety of an individual degradation product
or a given degradation profile at the level(s) specified and the first step in qualification of impurities is to conduct the minimum genotoxicity screening.
Plasma concentration of cross-linked fibrin degradation product
(D-dimer) and the risk of future myocardial infarction among apparently healthy men.
* In most cases, acetone (residual solvent or rubber oxidation product) and bromomethane (radical rubber degradation product
) can be found prior to any sterilization.
However, this method cannot separate crotonoylbetaine (impurity A) (Figure 1(b)), a major impurity and degradation product
, from L-carnitine .
Many researchers have repeatedly shown that a 30 kDa degradation product
of troponin-T increases with muscle ageing and is associated with tenderization.
This study aims to develop and fully validate a rapid, simple, and accurate HPLC-DAD method to quantify STP in the presence of its degradation product
in bulk and pharmaceutical dosage form.
Western blot analysis using the antibodies of the clinical immunoassay identified the first cTnT peak at [V.sub.R] of 5 mL as a degradation product
of cTnT with an M[W.sub.est] of 29 kDa (Fig.