demethylation


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demethylation

[de‚meth·ə′lā·shən]
(organic chemistry)
Removal of the methyl group from a compound.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The hydrolysis of TSM under acidic conditions involves in the cleavage of the sulfonylurea bridge and demethylation of the methoxy group.
Fungicide formulations that combined demethylation inhibitor and quinone outside inhibitor fungicides significantly increased yield response.
Second place went to Beom Jin Jayden Park and Hawra Al-Saygh for their project 'Effect of aspartame on kinetics of calf intestinal alkaline phosphatase' and third place went to Youssef Kanbour for 'Re-expression of BRCA1 using targeted DNA demethylation in breast cancer cells'.
Second place went to Beom Jin Jayden Park and Hawra Al-Saygh for their project, "Effect of aspartame on kinetics of calf intestinal alkaline phosphatase," and third place went to Youssef Kanbour for "Re-expression of BRCA1 using targeted DNA demethylation in breast cancer cells."
Since the studies are ongoing on association between DNA methylation and their consequences in the presentation of CHD, it is expected that the newly developed tools like next generation sequences techniques and further workout on demethylation phenomenon may help us to explore new ways in sorting out the exact epigenetics mechanism of CHD thus helping us in the treatment of complicated heart diseases.
Homocysteine (Hcy), formed after methionine demethylation, is a sulfur containing amino acid.
Later, many enzymes regulating histone demethylation were discovered.
Citation: Jose Luis Sardina et al., Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.
Accumulation of iHg in these organs after exposure to MeHg may suggest a demethylation process.
In addition, we studied the effect of conditioned medium from normal and senescent fibroblasts cells on colon cancer cell proliferation and DAC-induced DNA demethylation. This study was performed using our recently described demethylation reporter, HCT116-pFLJ-H2B cells, henceforth referred to as HCT116 [31].