demyelination


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Related to demyelination: vasculitis, Demyelinating diseases

demyelination

[dē‚mī·ə·lə′nā·shən]
(pathology)
Destruction of myelin; loss of myelin from nerve sheaths or nerve tracts.
References in periodicals archive ?
Demyelination secondary to chronic nerve compression injury alters Schmidt-Lanterman incisures.
In either of these two CS-treated groups, LFB staining showed significant decrease of demyelination in brain parenchyma compared with control group [Figure 4]a,[Figure 4]b,[Figure 4]c,[Figure 4]d,[Figure 4]e,[Figure 4]f.
11) Demyelination can leave a patient with motor and sensory deficits.
Psychotic symptoms arise from regional demyelination simultaneously with MS.
Brain biopsy has an importance in the differential diagnosis of primary central nervous system lymphoma (PCNSL) and inflammatory demyelination while any suspected contrast-enhanced white matter lesion was examined [11].
Demyelination in the cuprizone model is an early observable event without damaging other CNS cell types; besides oligodendrocytes and without provoking the breakdown of the blood brain barrier and subsequently causing the invasion of lymphocytes.
Most patients note visual disturbances, secondary to optic nerve necrosis or demyelination, as one of the first symptoms3.
Demyelination and inflammation both occur in the current mouse model of MS and result in progressive paralysis beginning in the tail.
The pathological changes in diabetic neuropathy are so complicated, that some studies have cited electrophysiological and pathological evidence of segmental demyelination as the primary lesion.
1] Increased psychosine levels lead to widespread destruction of oligodendroglia and impaired Schwann cell function in the central and peripheral nervous systems and to subsequent demyelination.