demyelination

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demyelination

[dē‚mī·ə·lə′nā·shən]
(pathology)
Destruction of myelin; loss of myelin from nerve sheaths or nerve tracts.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Caption: FIGURE 3: Allogeneic mASCs reduce demyelinization and inflammatory infiltration in the central nervous system during EAE progression.
This progressive demyelinization is initially an inflammatory process that ultimately leads to the destruction of the nerve.
Electrodiagnostic studies ruled out demyelinization.
Electrodiagnostic studies ruled out demyelinization. The reports prompted an update from the CDC, suggesting that the paralysis syndrome deserves careful consideration in the diagnosis of the virus (JAMA 288[15]:1839-40, 2002).
Inhalant abuse can also cause widespread, permanent brain damage; toluene can cause demyelinization in the brain and peripheral nervous system.
Gene-nutrient interactions that compromise normal one-carbon metabolism are associated with increased risk of cardiovascular disease (2), certain cancers (8), birth defects (9, 10), recurrent early pregnancy loss (11), central nervous system demyelinization (12), and neuropsychiatric disease (13, 14).
The process of vanishing myelin is called demyelinization.[2]
Other suggested factors include demyelinization by HIV-infected glial cells, blocking of neuroleukin binding, dysfunction of the blood-brain barrier, and increased intracellular neuronal calcium.
(17,21) Nonseptic encephalomyelitis was seen in some cases, and mild to severe demyelinization in the brain was also a common pathologic finding.
As part of these responses, glial TLRs, connexin hemichannels (Cx HCs), pannexin (Panx) channels might be key players in acute and chronic neurodegenerative diseases characterized by open BBB, demyelinization, and neuronal degeneration [11].