denature

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denature

[dē′nā·chər]
(chemistry)
To change a protein by heating it or treating it with alkali or acid so that the original properties such as solubility are changed as a result of the protein's molecular structure being changed in some way.
To add a denaturant, such as methyl alcohol, to grain alcohol to make the grain alcohol poisonous and unfit for human consumption.
References in periodicals archive ?
With the use of constant denaturing capillary electrophoresis, formation of HDs was demonstrated and a simple "reconditioning PCR" suggested (Jensen 1993; Thompson & Marcelino 2002) to reduce the number of HDs produced.
PCR conditions for pap31 gene amplification were a single hot-start cycle at 95[degrees]C for 5 min, followed by 45 cycles of denaturing at 94[degrees]C for 45 s, annealing at 58[degrees]C for 45 s, and extension at 72[degrees]C for 45 s.
Indeed, if we allow that small business can be specific in nature, we must also allow for the corollary of this statement, namely denaturing.
Hetero-duplex formation was obtained by mixing together, denaturing, and gradually reannealing equimolar quantities of PCR products for patients and controls.
Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA.
The nondenaturing electrophoresis system has nearly the same resolution as that obtained with denaturing acrylamide gels and silver staining.
KEY WORDS: exclusive PCR; denaturing gradient gel electrophoresis: cry4 gene; Bacillus thuringiensis.
But their underlying structure is linear, and that makes them susceptible to unfurling, or denaturing.
EPIEN's products employ a patented chemical denaturing system to more effectively cleanse wound tissue of bacteria and cell debris while reducing the patient's pain and inflammation.
The use ofbiocompatible options brings a streamlined approach to denaturing DNA and semi-preparative proteomics separations.
Mutation detection sensitivity obtained with endoVII digestion was found to be similar to that for denaturing HPLC and direct sequencing (13).
Denaturing polyacrylamide gel materials were obtained from National Diagnostics (Atlanta, GA).