dengue fever

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dengue fever

(dĕng`gē, –gā), acute infectious disease caused by four closely related viruses and transmitted by the bite of the female Aedes mosquito; it is also known as breakbone fever and bone-crusher disease. The disease occurs in both epidemic and sporadic form in warm climates (S United States, South America, the E Mediterranean countries, India, and especially SE Asia and the W Pacific). The classic symptoms, following an incubation period of five to eight days, are high fever, chills, severe headache, pain in the joints, pain behind the eyes, rash, sweating, and prostration, but infected persons may experience milder symptoms. Symptoms subside in two to four days, but after a remission lasting from a few hours to two days there is another rise in temperature, and a generalized rash appears. Convalescence is sometimes prolonged, with weakness and low blood pressure.

Dengue hemorrhagic fever, a severe form of the disease, can cause hemorrhage, shock, and encephalitis. It can occur when a person who has acquired immunity to one of the viruses that cause dengue fever is infected by a different dengue virus; antibodies to the first dengue infection apparently work to aid the second virus. It is a leading cause of death among children in Southeast Asia and in recent years has become increasingly prevalent in tropical America. There is no specific treatment for dengue fever except good nursing care. Both diseases can be controlled by eradicating the mosquitoes and destroying their breeding places. The mosquito population also has been controlled through the release of sterile male mosquitoes and the release of mosquitoes infected with bacteria that makes the insects incapable of transmitting viruses.

Dengue fever

[′deŋ·gē ‚fēv·ər]
An infection borne by the Aedes female mosquito, and caused by one of four closely related but antigenically distinct Dengue virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). It starts abruptly after an incubation period of 2-7 days with high fever, severe headache, myalgia, and rash. It is found throughout the tropical and subtropical zones. Also known as break-bone fever.
References in periodicals archive ?
Results: Overall, 33,577 specimens tested for dengue virus.
Detection of all four serotypes of Dengue virus in positive pools of larvae in A.
Angel & Joshi (9) have detected dengue virus in individual mosquito head squashes and the remnants of positive mosquitoes have been used in cell culture and mice inoculation followed by IFA.
Serotype specific dengue virus primers targeting C-prM gene junction were designed according to method described by Fatima et al.
The researchers continued to investigate the role of mast cells in attacking dengue virus in humans, and identified a biomarker - a mast cell-derived product - that appeared to predict the illness' most severe cases in human patients.
aegypti screened by ELISA and IFA, 15 pools, collected in April, June-July, November-December in 2003 and March, May in 2004, were found positive for dengue virus infection.
The Chief Minister appreciated their total support to the provincial government adding he was looking forward for replicating successful models of other countries in order to control dengue virus in Peshawar and other suspected districts of the province.
Tharparkar -- The outbreak of dengue virus could not be controlled in Tharparkar as four more patients were contracted virus and toll reached to 261.
Abstract Dengue virus has now become a serious threat to humans.
LAHORE -- Uncontrolled and rapid outspread of dengue virus has added to the miseries of people of Punjab besides posing serious threat to public lives as nine new cases were reported across the province on Thursday, raising the toll to 2,589.