MSCs (DFSCs) may be an option for the regenerative and anti-inflammatory treatment of ALS because of their potential to differentiate into neuron-like cells (13) and their high ability in the immunosuppression against inflammatory responses.
Immunomodulatory properties of mesenchymal stem cells derived from dental pulp and dental follicle
are susceptible to activation by toll-like receptor agonists.
In our study, for all samples, the dental follicle
width measured was 3.13 mm, and, according to the literature, our results were in the normal range.
They develop within the normal dental follicle
around an unerupted tooth as a result of fluid accumulation between the follicular epithelium and the crown of the tooth.16
Due to its nonexclusive histological features, this lesion is often confused with other entities, such as hyperplastic dental follicles
, odontogenic myxomas, and desmoplastic fibromas, which highliaght the importance of clinical pathological correlation in the diagnosis of odontogenic fibromas.
(8) The basic difference between simple and WHO type is that the stroma of the simple fibroma mimics that of a dental follicle
from which it is probably derived.
Pellets of human dental follicle
cells have been reported to be able to regenerate critical size bone defects in rats' calvaria .
If the dental follicle
is found to be uninvolved during surgery and if it can be easily separated from the tumor, it may be possible to remove the lesion while leaving the teeth in place .
Caption: Figure 2: (A) The initial periapical radiography showing no periapical alterations in (51) and lesion in (61) with disruption of the dental follicle
of the permanent left maxillary central incisor (21).
Carbone et al., "Osteogenic differentiation of dental follicle
stem cells," International Journal of Medical Sciences, vol.
Mononuclear cells (osteo-clast precursors) must be recruited into the dental follicle
prior to the onset of eruption.
Furthermore, pathologies of the dental follicle
, interfering with tooth eruption have been reported [Kim et al., 2008].