desmin


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Related to desmin: Titin, vimentin

desmin

[′dez·mən]
(biochemistry)
The muscle protein forming the Z lines in striated muscle.
References in periodicals archive ?
Desmin ensheathment ratio as an indicator of vessel stability: evidence in normal development and in retinopathy of prematurity.
In the present case report, the diagnosis of myolipoma was based on histological findings, showing the presence of mature adipose tissue and well-differentiated spindle-shaped cells that were positively stained for desmin and actin, confirming its smooth muscle origin.
Parameter Value Pan-cytokeratin AE1/AE3 + Pan-cytokeratin MNF116 - Epithelial membrane antigen (EMA) - CD31 - CD34 - FLI1 + ERG + SMA Focal Desmin - MyoD1 - S100-protein - HMB-45 - Melan-A - MiTF - INI1 + CAMTA1 -
Myofibroblastic DL can also be mistaken for a smooth muscle neoplasm owing to its frequent expression of smooth muscle actin and desmin. Pathologists should be aware of this variant of DL to avoid misdiagnosis.
Analysis showed strong immunoreactivity for [alpha]-smooth muscle actin (Figure 7A), desmin (Figure 7B), and vimentin (Figure 7C).
In addition to renin--angiotensin pathway examination, the current study has investigated the effect of EDs on the mRNA expression levels of certain genes associated with normal kidney function and stability such as desmin and renal hypoxia marker erythropoietin (EPO).
Caption: Figure 3: Immunohistochemical stain for desmin showing scattered intratumoral positive cells (arrowhead), magnification = 400 x.
Immunohistochemically, they differ from other mesenchymal tumors by CD34 (+), C-kit (+), discovered on GIST-1 (+), desmin (+/-), SMA (+/-), CD31 (-) and S100 (-) staining.
Positivity for desmin, vimentin, and SMA are variable and S100 immunoreactivity is rare in glomus tumors (1, 9, 10).
The case discussed here was MIC2 positive and negative for CK, LCA, desmin and synaptophysin, suggestive of Ewing Sarcoma.
To examine the possible correlation of PPAR[gamma] with hepatic fibrosis, the correlation between the expression levels of PPAR[gamma] and other two markers of fibrosis, [alpha]-SMA and desmin, was measured.
Angioleiomyomas have an identical immunophenotype to leiomyomas of deep soft tissue, being positive for SMA and desmin and negative for S100 protein [17].