desmolase

desmolase

[′dez·mə‚lās]
(biochemistry)
Any of a group of enzymes which catalyze rupture of atomic linkages that are not cleaved through hydrolysis, such as the bonds in the carbon chain ofD-glucose.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Moustafa and colleagues in a well designed trial involving 12 male human subjects has shown that radiofrequency fields of cellular phones generated free radicals that increased peroxidation in human plasma and decreased the activities of the antioxidant system as superoxide desmolase and total glutathione peroxidase in human erythrocytes.
This stimulates production of cyclic AMP (cAMP) an intracellular messenger that induces intracellular changes to promote transport of cholesterol to the mitochondria where it is converted to pregnenolone by an enzyme known as desmolase. Pregnenolone is the rate-limiting precursor for testosterone and other steroid hormones.
cholesterol, the precursor for all steroid hormones, is converted first into 20 [alpha]-hydroxycholesterol by 20 [alpha]-hydroxylase and then into pregnenolone by desmolase. Pregnenolone can enter various biochemical pathways, resulting in the synthesis of mineralocorticoids (e.g., aldosterone), glucocorticoids (e.g., cortisol), androgens (e.g., testosterone), and estrogens (e.g., estradiol-17[beta]).